yes they do but there is no need to use it unless you are in renal failure..
Patients with chronic kidney disease (CKD) Stages 3-5 experience decreased calcitriol (1,25 (OH2)[D.sub.3]) levels when the kidney can no longer convert Vitamin D to its active form (Parker, 1998). Although most often associated with suppression of parathyroid hormone (PTH), Vitamin D performs a multitude of other body functions; among them, suppression of renin expression, modulation of the immune and inflammatory system, and promotion of vascular endothelial health (Teng et al., 2005).
Pharmaceutical Vitamin D analogues are available in oral form--Rocaltrol (calcitriol) (Roche; Nutley, NJ), Hectorol (doxercalciferol) (Genzyme Corporation, Cambridge, MA), or Zemplar[TM] (paricalcitol) (Abbott Laboratories, Abbott Park, IL)
Injectable form--Hectorol, (Genzyme Corporation, Cambridge, MA), Calcijex[R], and Zemplar[TM] (Abbott Laboratories, Abbott Park, IL). Of note is that oral paricalcitol (Zemplar[TM]) does not carry an indication for patients with CKD Stage 5. Although the price for injectable vitamin D is higher than that of oral products, clinicians prefer it for patients on hemodialysis for several reasons.
1. Intravenous (IV) Vitamin D is perceived as having superior efficacy and fewer side effects than oral preparations.
2. Administering Vitamin D IV while patients are on hemodialysis is convenient for patients and providers and the exact dosage received is quantifiable (Nephrology Pharmacy Associates, 2000).