Instant Anxiety after switching from Test E to Test Prop

[Siggy]

A long 500MG of Test Enanthate cycle of about 12 months has been my go to blast for the 8 years I been dabbling in this hobby. The first couple of times I blasted this cycle, I felt great mentally. It was almost like being on a trace amount of adderall for the entire cycle. The last time I began this blast was this January. I haven’t felt particularly amazing this time around, just normal (which I do welcome and I did feel good). I used an Ai on my first cycle but have not used one since. I haven’t needed it, no Gyno and have felt great with no sides.

I had begun to run out of Enanthate and had a bunch of Test Propionate laying around. Not wanting to pin every day, I decided to make a 250 Enanthate/200 Propionate mix that I administer 3 times per week Mon, Wed and Friday for a total of 450MG weekly.

Been on this mix for about 6 weeks now and basically, instant anxiety since the beginning.

Yea, there was a small window of time there where I was well over 500MG as the long ester was still in my system and the fast ester quickly saturated me, but we are well past that point.

My theory is that my body was used to running on a large dose of Estrogen via aromatase and the fast absorbing Prop significantly reduced the estrogen level.

I have also experienced a drop in libido. Its still there but definitely reduced.

Anyone else experience anything similar?

 

[Muay Thai]

Everyone here who has any sense of mind is going to tell you to get bloodwork to rule things out in a process of elimination before 'you start guessing and assuming which the culprits (If any) are.

thousands of us have switched from a long ester test to a short ester like prop without this happening.

prop is not directly going to reduce estrogen, the switch may results in less aromatization if that's what you meant specifically bro

personally, any time I switch to quick esters I experience some sort of disarray bodily and discomfort

 

[Fa Seeshus]

You could be having a differing dht response on the prop. That works usually increase libido though.

 

[thethinker48]

Get bloodwork

Androgen exposure also increases amygdala activation overtime, so if you're prone to anxiety, steroid use overtime will increase anxiety (ie what you felt before and what you feel now can be different)

 

[slesh]

Everyone here who has any sense of mind is going to tell you to get bloodwork to rule things out in a process of elimination before 'you start guessing and assuming which the culprits (If any) are.

thousands of us have switched from a long ester test to a short ester like prop without this happening.

prop is not directly going to reduce estrogen, the switch may results in less aromatization if that's what you meant specifically bro

personally, any time I switch to quick esters I experience some sort of disarray bodily and discomfort

This^

 

[Siggy]

Everyone here who has any sense of mind is going to tell you to get bloodwork to rule things out in a process of elimination before 'you start guessing and assuming which the culprits (If any) are.

thousands of us have switched from a long ester test to a short ester like prop without this happening.

prop is not directly going to reduce estrogen, the switch may results in less aromatization if that's what you meant specifically bro

personally, any time I switch to quick esters I experience some sort of disarray bodily and discomfort

Yea, I meant there should be lower estrogen via reduced aromatase.

 

[stackdizzy]

Are you sure what you're running is prop? Could just be he ester, obviously something is going on your body doesn't like. If you have another bottle of prop see if that bottle does the same thing and of course depending how bad exactly your anxiety is. If its you winding up in the hospital bad. I just would take a different ester. If they give you pills at the Dr office to combat this anxiety you will in the future regret taking head meds just to take certain anabolics. Trust me on this!! I've known people that only take cyp for years and years. I would only take a benzo for anxiety personally but some people would say not even to do that!

 

[Sj9]

My theory is it’s the sudden increase in androgens versus your body acclimating to a steady-state with the longer esters. You’re not the first person I’ve seen claim they feel this way after reading various anecdotal reports across different forums.

I started experimenting with the propionate ester for the first time at the start of the year and noticed something similar, although I wouldn’t describe it as a true feeling of anxiety but I could liken it to be amped up by a good amount of caffeine, ephedrine or other stimulants, at least up until mid-late afternoon which is when I guess the T levels taper off for me.

It was a very noticeable difference for me even at 10mg of propionate daily, and I don’t feel anything similar at much higher dosages of T Enanthate. There is somewhat of an energy drop-off later in the evening too though which I guess can be looked at as both a positive & negative. When I misunderstood the ester’s pharmacokinetics and was injecting before going to sleep I had poor sleep nightly.

I’ve noticed similar things with oral methenolone acetate versus the injectable Enanthate ester. I’ve used 700+mg of the injectable per week and felt like I was on nothing but the Test I was also using, but tiny dosages of the acetate ester orally felt like taking a strong DHT-derivative (all of which I’ve strangely become very sensitive to in the past two years), and I felt way too stimulated on it to focus on anything outside of the gym.

 

[Black Beard]

A long 500MG of Test Enanthate cycle of about 12 months has been my go to blast for the 8 years I been dabbling in this hobby. The first couple of times I blasted this cycle, I felt great mentally. It was almost like being on a trace amount of adderall for the entire cycle. The last time I began this blast was this January. I haven’t felt particularly amazing this time around, just normal (which I do welcome and I did feel good). I used an Ai on my first cycle but have not used one since. I haven’t needed it, no Gyno and have felt great with no sides.

I had begun to run out of Enanthate and had a bunch of Test Propionate laying around. Not wanting to pin every day, I decided to make a 250 Enanthate/200 Propionate mix that I administer 3 times per week Mon, Wed and Friday for a total of 450MG weekly.

Been on this mix for about 6 weeks now and basically, instant anxiety since the beginning.

Yea, there was a small window of time there where I was well over 500MG as the long ester was still in my system and the fast ester quickly saturated me, but we are well past that point.

My theory is that my body was used to running on a large dose of Estrogen via aromatase and the fast absorbing Prop significantly reduced the estrogen level.

I have also experienced a drop in libido. Its still there but definitely reduced.

Anyone else experience anything similar?

Prop hits HARD and FAST. Contrary to popular belief based on an old study, testosterone propionate peaks around 4 hours. The study didn't actually test hour to hour levels as far as i know and erroneously reports a peak at around 12 hours.



Personally, just 50 mg Test prop to deltoid with insulin needle nets me around 5,000 ng/dL total testosterone at 4 hour peak. A very short lived peak. At 24 hours, i go from 5,000 ng/dL to 1,300 ng/dL. At 24 hours, my estradiol is around 90 pg/mL.



You can see how these fluctuations and massive peaks in T, E2 and DHT could cause someone to feel more "amped up" on propionate. I feel way better on prop and much dryer for blast or TRT. Your body isn't used to that huge spike in hormones which might be the issues, but some guys just feel like dogshit on propionate and some feel like dog shit on cyp/enanthate.


You also have the variable of using both Long ester and short ester T at the same time, so it might just be that all your hormone levels are all extremely elevated, you are possibly going to see HUGE spikes in T, DHT, E2 . Your result might be different if you were only running prop on its own.

 

[bbxtreme]

A long 500MG of Test Enanthate cycle of about 12 months has been my go to blast for the 8 years I been dabbling in this hobby. The first couple of times I blasted this cycle, I felt great mentally. It was almost like being on a trace amount of adderall for the entire cycle. The last time I began this blast was this January. I haven’t felt particularly amazing this time around, just normal (which I do welcome and I did feel good). I used an Ai on my first cycle but have not used one since. I haven’t needed it, no Gyno and have felt great with no sides.

I had begun to run out of Enanthate and had a bunch of Test Propionate laying around. Not wanting to pin every day, I decided to make a 250 Enanthate/200 Propionate mix that I administer 3 times per week Mon, Wed and Friday for a total of 450MG weekly.

Been on this mix for about 6 weeks now and basically, instant anxiety since the beginning.

Yea, there was a small window of time there where I was well over 500MG as the long ester was still in my system and the fast ester quickly saturated me, but we are well past that point.

My theory is that my body was used to running on a large dose of Estrogen via aromatase and the fast absorbing Prop significantly reduced the estrogen level.

I have also experienced a drop in libido. Its still there but definitely reduced.

Anyone else experience anything similar?

The same would apply here as it does for tren as Testosterone is androgenic. I outlined this in my recent thread on here.

High androgens will stress mast cells leading to an excess of histamine (along with hormone fluctuations as others have said).

High levels of histamine can lead to increased nervous system activity and heightened anxiety.

Try adding DAO if you want to run prop and see if helps, if so you’ve found the issue.

But IMO if you don’t respond well to prop just use cyp or enanthate instead. I get the draw of both, but this sport is about sustainability.