Local growth from AAS bases

[Biggerp73]

local hormone application similarly isn’t a likely stimulant, since muscle cells won’t ingress stimulating hormones from a random oil pocket, they ingest it from the bloodstream.

That's something I've thought about before

How are transdermals different? From what I remember, local effect of transdermals is pretty commonly accepted - not for site-specific AAS-induced skeletal muscle growth, but for other things

 

[Virtuous]

That's something I've thought about before

How are transdermals different? From what I remember, local effect of transdermals is pretty commonly accepted - not for site-specific AAS-induced skeletal muscle growth, but for other things

The mechanism of cellular interaction for hormonal Anabolics compared to, say, a local anesthetic are pretty different.

 

[Type-IIx]

That's something I've thought about before

How are transdermals different? From what I remember, local effect of transdermals is pretty commonly accepted - not for site-specific AAS-induced skeletal muscle growth, but for other things

With transdermals you get aggregation of the AAS in the stratum corneum (within the skin) which, for example with scrotal application, can lead to increased DHT (with test) in the prostate due to local 5α-reductase activity in the tissues in the area.

With intramuscular injections of unesterified AAS, you still get the classical absorption/distribution/metabolization/excretion as with esterified compounds, i.e., dissolution into the blood of the circulatory system where the androgen can do its thing systemically.

 

[Biggerp73]

With transdermals you get aggregation of the AAS in the stratum corneum (within the skin) which, for example with scrotal application, can lead to increased DHT (with test) in the prostate due to local 5α-reductase activity in the tissues in the area.

With intramuscular injections of unesterified AAS, you still get the classical absorption/distribution/metabolization/excretion as with esterified compounds, i.e., dissolution into the blood of the circulatory system where the androgen can do its thing systemically.

I was thinking of how people will use topical DHT for penis enlargement actually

 

[jaxino]

Bah i have used lots of Stanolone homemade by me ..... Not worth. "Stick to the basic" always works.

Masteron on other hand seems to give some "penis gains".

 

[b-boy]

Lol damn I wish victor black was still here, this is the type of bro shit passed around message boards that he despises.

 

[Fit2Serve]

Agreed, if it worked well pros would not have weak Bodyparts, just calves full of tren base lol

oh man dont say that to the guys that think they can bring up lagging bodyparts.
man i hate those threads....