I've seen a lot of sick people over the last 25 years. I'm trying to remember who I've seen with CKD, or more specifically CKD requiring dialysis, without comorbid hypertension or a genetic pathology. I'm not saying it doesn't exist. I'm just saying I'm having trouble thinking of that person right now. Maybe I've never seen it, which is my point. This includes bodybuilders I've met or known on some personal level like Don Long (HTN, diuretics), Beau Baisden (HTN, diuretics, partying in Vegas :headbang
, Tom Prince (NSAIDs + HTN + diuretics), Flex Wheeler (HTN + diuretics), Dan Duchaine (polycystic kidney disease), Mike Morris (HTN, diuretics) and regular run of the mill people I've treated in the old charity hospital system in South Louisiana to the most privileged at Cedars Sinai.
They all have HTN = hypertension usually coupled with something else. NSAID abuse, diuretic abuse, cocaine abuse, all of the above, etc.
My point is, monitor your BP yourself at home regularly with a reliable cuff and keep in check. Risk begins over 115 systolic. If you have some measure of CAD already this may to be too low for you and you would aim higher, 120-130. Don't do stupid shit like take 3 grams of ibuprofen per day (Prince) or snort an 8 ball of coke in a night the weekend of the O (Beau) on top of your untreated hypertension (all of them). Avoid loop diuretics like Lasix and Demedex (Chad Nicholls' choice - Prince, Flex). Use Aldactone sparingly pre contest only as needed if you must use a diuretic. Do not use it to look better for guest posing or Vegas pool parties like I've known a lot these guys to do. If you are a water logged fuck you're probably fat anyway. How many water logged fucks have you known that shoot Lasix or take Demedex come in shredded and win the show as a result? Almost never happens. I'm not saying it can't, I'm just saying I'm having trouble thinking of that person right now.
Avoid any and all of that and you will have a hard time convincing me that you have to worry about the direct affect of androgens on the kidneys aka androgenic nephrotoxicity. Show me a guy with a BP of 106/65 for example with CKD. It will be very diifficult to find this person.
Rex.