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Metformin Recalled Due To Cancer-Linked Contaminants

danieltx

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You have to really wonder about what's going on in the supply chain given we've had recalls of blood pressure medications, Zantac, and now metformin all for the same thing.

https://www.msn.com/en-us/health/ot...of-diabetes-drug/ar-BB14M1cd?ocid=hplocalnews

https://www.msn.com/en-us/money/com...-tainted-diabetes-drug/ar-BB14LJJC?li=BBnb7Kz

U.S. health regulators are telling five drugmakers to recall their versions of a widely used diabetes medication after laboratory tests found elevated levels of a contaminant linked to cancer.

The Food and Drug Administration said late Thursday that several batches of the drug metformin tested positive for unsafe levels of a chemical called N-Nitrosodimethylamine. The agency has stepped up testing after the chemical was found in dozens of shipments of heartburn drugs last year, triggering recalls of Zantac and other popular over-the-counter and prescription medications.

Metformin tablets are a staple of diabetes care, reducing excess sugar in the blood. People with Type 2 diabetes use metformin alone or with other drugs to help control their blood sugar levels. More than 34 million people in the U.S. have this disease.

Patients should continue taking metformin drugs until their doctor can prescribe a replacement, the FDA said in a statement, noting the risks of discontinuing. Regulators are still assessing whether the recalls will lead to shortages of metformin, but noted that a number of other companies make generic versions of the drugs that don't appear to be affected by the issue.

Drugmaker Apotex Corp. recalled its extended-release metformin distributed in the U.S. earlier this week after the FDA found contamination in one lot. Apotex said in a statement it recalled all supplies of the drug “out of an abundance of caution.” The company said it stopped selling the drug in the U.S. in February 2019 and that little remains on the market.

The FDA announcement did not name the four other drugmakers who have been requested to recall their products.

The agency noted that no contamination problems have been found in immediate-release metformin.

The FDA is responsible for ensuring that medicines for the U.S. market are made in safe, sanitary conditions that meet federal quality standards. But government inspectors have repeatedly criticized the agency for falling short in reviewing overseas manufacturing plants as the pharmaceutical supply chain has increasingly spread to Asia.

In March, the FDA suspended nearly all U.S. and foreign inspections due to safety concerns and travel restrictions caused by the coronavirus outbreak.[/url]
 

maldorf

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maldorf

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"During the last 13 months, the FDA has had to announce more than 50 recalls of blood pressure medications because the active ingredient valsartan contained jet-fuel contaminants estimated to cause cancer in one out of every 8,000 pill takers. Who supplies it? China."


"In 2008, a contaminated blood thinner from China, heparin, killed 81 American patients. Heparin is made from the mucous membranes of pig intestines. In China, slaughtered pigs are often cooked in unregulated family workspaces to begin the process."
 

prodaf

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Gunsmith

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Hopefully not too much longer. I think we learned a valuable lesson from this event.
You would think that would be the case , but at the end of the day the dollar rules and the pharmaceutical companies will always outsource and get their raw materials from the cheapest sources.
 

propp

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I really hope all this is going to make companies make product in US things have to change … even though I know they probably wont
 

maldorf

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I'm willing to pay more for US products
A combo of that and out sourcing to countries other than China will do the job. Right now we have "all our eggs in one basket."
 

kilsong

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In China, slaughtered pigs are often cooked in unregulated family workspaces to begin the process."
WHAAAAAT?? So they don't even have to regulate where they get their first step raw materials to make our raw materials???
That's incredible.
And that's where our American drug companies get their raws. What the fuck....
 

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