- Joined
- Oct 20, 2020
- Messages
- 1
Factors Other than Sex Steroids Modulate GHRH and GHRP-2 Efficacies in Men
www.ncbi.nlm.nih.gov
"Conclusion: During fixed T/E2 availability, AVF (Visceral Fat) contributes 41% of the GH-response variability to maximal GHRH drive, whereas IGF-I accounts for 31% of that for GHRP-2. Accordingly, a statistically equalized sex-steroid milieu permits dissection of age-independent and T/E2-independent modulators of GHRH and GHRP efficacy in men"
Has anyone ever contrasted peptides efficiency with a fixed TRT dose as compared to a blast dose? I was thinking of trying this after my next PL competition (will be below 7%) a large dose of (200mcg of each) Hex/Mod-GRF with (150mg) Test Suspension just 3x per week, two weeks on one week off. Ive got a long (16monht) off season and the return on investment from GH is low with a high cost, so I want to go back to hex and humalog preworkout but im worried its going to stall.
Really interested in
1) Has anyone tried this comparison?
2) Has anyone found a dosing protocol that mitigates hexarelin desensitization?
3) Do we have ample evidence to support orals would either increase GH pulsatiles or would they influence IGF to help with a hex induced refractory period?
Thanks
@Mike Arnold
Factors Other than Sex Steroids Modulate GHRH and GHRP-2 Efficacies in Men: Evaluation Using a GnRH Agonist/Testosterone Clamp - PMC
Background: Sex steroids are prominent regulators of pulsatile GH secretion. Hypothesis: An experimentally controlled sex-steroid milieu will permit detection of nonsteroidal factors that determine GH secretion. Subjects: Eleven young (age, 24 ± ...
www.ncbi.nlm.nih.gov
"Conclusion: During fixed T/E2 availability, AVF (Visceral Fat) contributes 41% of the GH-response variability to maximal GHRH drive, whereas IGF-I accounts for 31% of that for GHRP-2. Accordingly, a statistically equalized sex-steroid milieu permits dissection of age-independent and T/E2-independent modulators of GHRH and GHRP efficacy in men"
Has anyone ever contrasted peptides efficiency with a fixed TRT dose as compared to a blast dose? I was thinking of trying this after my next PL competition (will be below 7%) a large dose of (200mcg of each) Hex/Mod-GRF with (150mg) Test Suspension just 3x per week, two weeks on one week off. Ive got a long (16monht) off season and the return on investment from GH is low with a high cost, so I want to go back to hex and humalog preworkout but im worried its going to stall.
Really interested in
1) Has anyone tried this comparison?
2) Has anyone found a dosing protocol that mitigates hexarelin desensitization?
3) Do we have ample evidence to support orals would either increase GH pulsatiles or would they influence IGF to help with a hex induced refractory period?
Thanks
@Mike Arnold
