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Prednisolone for muscle building

Joltan

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Jan 16, 2015
Messages
424
Anyone ever try this? I came across the following article, and it mentions that prednisone when taken in weekly doses actually helps build and repair muscle. It is well known that taking Prednisone daily is catabolic, but apparently not if taken weekly.

Excerpt:
Prednisone direct the producution of annexins, proteins that stimulate muscle healing. Giving weekly doses stimulate a molecule called KLF15, which is associated with improved muscle performance. Mice with muscular dystrophy that received weekly prednisone were stronger and performed better on the treadmill than those that received a placebo. When prednisone was given every day, the muscles atrophied and wasted.


 

FredthePunisher

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Mar 13, 2022
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I had read an interview somewhere of Phil heath and he talk about it, that it take if I remember well 3 months a row per year with other drugs in his off season for mass gains
 

trackstar19

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Jul 1, 2012
Messages
245
Fuck prednisone. I’ve had to take it high dose (60mg) for months on end for an autoimmune disease … never again. I don’t believe it would aid in anabolism one bit, either, frankly. It is pure catabolism and fat accrual in pill form. Some studies theorize or use interesting data points to extrapolate and make their points … prednisone is hell and the opposite of anabolic and I wouldn’t trust the pros to outweigh the cons with it aiding in anabolism in some weird way with infrequent dosing.
 

heavyhitter

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Sep 12, 2004
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I would never purposely use prednisone
 

alfresco

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If the absence of your ache’s and pains allows you to train ‘normally’ then it could help. But in the absence of such, or for anything other than medical reasons, I would not take it (I have many a time).

It is a wonder drug for what it is prescribed for but like others have said, long term usage may have a place but I would try to avoid it.

I have talked about it, my usage, in depth in another thread. Some aspects were not pretty 🙁
 

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