Prednisolone for muscle building

[Joltan]

Anyone ever try this? I came across the following article, and it mentions that prednisone when taken in weekly doses actually helps build and repair muscle. It is well known that taking Prednisone daily is catabolic, but apparently not if taken weekly.

Excerpt:
Prednisone direct the producution of annexins, proteins that stimulate muscle healing. Giving weekly doses stimulate a molecule called KLF15, which is associated with improved muscle performance. Mice with muscular dystrophy that received weekly prednisone were stronger and performed better on the treadmill than those that received a placebo. When prednisone was given every day, the muscles atrophied and wasted.

Weekly Steroids Strengthen and Repair Muscles - News Center

Weekly doses of glucocorticoid steroids, such as prednisone, help speed recovery in muscle injuries and repair muscles damaged by muscular dystrophy, according to a study.

news.feinberg.northwestern.edu

Intermittent glucocorticoid steroid dosing enhances muscle repair without eliciting muscle atrophy

Glucocorticoid steroids such as prednisone are prescribed for chronic muscle conditions such as Duchenne muscular dystrophy, where their use is associated with prolonged ambulation. The positive effects of chronic steroid treatment in muscular dystrophy ...

www.ncbi.nlm.nih.gov

 

[FredthePunisher]

I had read an interview somewhere of Phil heath and he talk about it, that it take if I remember well 3 months a row per year with other drugs in his off season for mass gains

 

[Joltan]

Daily or weekly?

 

[trackstar19]

Fuck prednisone. I’ve had to take it high dose (60mg) for months on end for an autoimmune disease … never again. I don’t believe it would aid in anabolism one bit, either, frankly. It is pure catabolism and fat accrual in pill form. Some studies theorize or use interesting data points to extrapolate and make their points … prednisone is hell and the opposite of anabolic and I wouldn’t trust the pros to outweigh the cons with it aiding in anabolism in some weird way with infrequent dosing.

 

[heavyhitter]

I would never purposely use prednisone

 

[alfresco]

If the absence of your ache’s and pains allows you to train ‘normally’ then it could help. But in the absence of such, or for anything other than medical reasons, I would not take it (I have many a time).

It is a wonder drug for what it is prescribed for but like others have said, long term usage may have a place but I would try to avoid it.

I have talked about it, my usage, in depth in another thread. Some aspects were not pretty