Super low SHBG - problem??

[dimethyl11]

Great info all around - thanks everyone

 

[Doitagain]

I don’t know whether low shbg is bad or not. Mine has been around 2 for years. I do know through running blood work that I need to pin frequently to keep levels stable. Even 2x/week on ester I’ll have large peaks and dips. I pin ED or 3x/week.

Extremely low SHBG = faster metabolic clearance rate of Testosterone (or any AAS actually).
This means that more frequent administration is advisable.

Indeed.

 

[Yousef12O2]

I honestly don't even want to waste precious minutes of my life watching these videos

This x1000

 

[cmryan]

Extremely low SHBG = faster metabolic clearance rate of Testosterone (or any AAS actually).
This means that more frequent administration is advisable.
Hypothyroidism can worsen the issue, so might overt low E2.

Just curious but by what mechanism does hypothyroidism and low E2 exacerbate clearance of test?

 

[Doitagain]

Just curious but by what mechanism does hypothyroidism and low E2 exacerbate clearance of test?

Both conditions lower SHBG further.