I have had a doctor tell me that some antibiotics can be taxing on the liver. Not that it has anything to do with your question but it might be something to think about if you using orals.
no it shouldnt..
the only antibiotic i would be worried about is the ones that fall in the fluroquinolone group such as cipro, oflaxo.. etc. and only because they are known to cause tendon damage. other than that i dont think one course of anitbiotic would do much damage.