The secret to taking tryp is that it has to be taken on an empty stomach. If not it will compete with LTyrosine and BCAA's to enter the blood brain barrier[where it is converted].One would have to take a butt load intravenously to induce GH release, if then.Prolonged use WILL raise many other plasma aminos,which is good.If one cant go to sleep very fast, it is melatonin that is needed, if one wakes up and cant go back to sleep,it is a lack of serotonin, both are made from LTryiptophan.Ever wonder why at times during the after none you will get very sleepy.After you eat lunch and especially one high in carbs,your body will release insulin, insulin will take almost all of the amino's and push them into your muscles and brain.Because tryp is weaker than all other aminos, it is left in the blood alone.After a couple of hrs it converts to serotonin and melatonin and causes you to get sleepy.Tryptophan and Tyrosine are neurotransmitters, any time you stress your body, drinking, drugs, exercising, not getting enough sleep,over work OR the one we lifters have to watch for OVER Training you delete your neurotransmitters.By taking LTryptophan and L Tyrosine you can work out more offten and with more intensity.I take tryp when I wake at about 12am to pee so I know its on an empty stomach,when I wake between 2am and 6am I take Tyrosine.About an hour after Tyrosine has been taken [or less] I can go back to sleep or work depending on what day it is.After a while your body gets in to a rhythm and you are healthier, happier and bigger.When I was younger I could work out 6 days a week and not over train.Now it takes longer to heal so I cant work out as many days in a row.I could always get bigger, faster than any one else. If you go out for a drink take 4000 mg Tryptophan on an empty stomach 1 hour before and see how fast you catch a buzz. That's why alcohol is a depressant it makes your body use all its serotonin.