- Joined
- Apr 9, 2021
- Messages
- 1,778
Peter Bond wrote a highly pertinent article here: Where are the myostatin inhibitors?
I would mention that good ol' testosterone attenuates Myostatin (decreases Mst expression and enhances β-catenin signaling, thereby ↑Fst expression, thereby inhibiting Mst) and functions via myriad other anabolic pathways.
Attenuation of myostatin has also been highlighted as an important factor by which β2-agonists (e.g., Clen) elicit hypertophy.
Myostatin does seem an interesting target, to induce hypertrophy & hyperplasia, as it is pluripotent.
I would mention that good ol' testosterone attenuates Myostatin (decreases Mst expression and enhances β-catenin signaling, thereby ↑Fst expression, thereby inhibiting Mst) and functions via myriad other anabolic pathways.
Attenuation of myostatin has also been highlighted as an important factor by which β2-agonists (e.g., Clen) elicit hypertophy.
Myostatin does seem an interesting target, to induce hypertrophy & hyperplasia, as it is pluripotent.