• All new members please introduce your self here and welcome to the board:
    http://www.professionalmuscle.com/forums/showthread.php?t=259
Buy Needles And Syringes With No Prescription
M4B Store Banner
worldofroids
Riptropin Store banner
Generation X Bodybuilding Forum
Buy Needles And Syringes With No Prescription
Buy Needles And Syringes With No Prescription
Mysupps Store Banner
IP Gear Store Banner
Anabolic Hormones Store Banner
Ganabol Store Banner
Spend $100 and get bonus needles free at sterile syringes
Professional Muscle Store open now
advertise1
PHARMAHGH1
Bruce Labs Store banner
gd
Professional Muscle Store open now
over 5000 supplements on sale at professional muscle store
roids-210x65-48kb-1
granabolic123
napsgear-210x65
advertise1
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
advertise1
PM-Ace-Labs
advertise1
kinglab
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store
over 5000 supplements on sale at professional muscle store

VERY tricky GH timing protocol question.

kilsong

Active member
Registered
Joined
Jun 7, 2012
Messages
570
I've been on 2iu TP Black Tops every night before bed for 7 weeks. My goal is to get to 4 iu daily.
The lathergy forced me to do them at nite before bed.
In the last week, I've uped to to 2.5 iu before bed. So far so good.
I want to follow conventional wisdom and do 2iu early am and then do some fasted cardio. And the remainder 2 iu later in the day.
My only problem is I work til 7 pm four days a week.. I'm in bed SLEEPING by 730 pm.
Additionaly, I go to the gym between 2-3 AM six days a week..
I would have just injected 2iu around 7 pm and my question is when to to take the other 2iu.
My goals are fat loss and new cell muscles.

I'm also running DHB about 400 /week...NPP/300 week.. and test cyp about 400/ week.
Any and all suggestions would be appreciated..
Thanks.
 

Type-IIx

Active member
Registered
Newbies
Joined
Apr 9, 2021
Messages
160
I've been on 2iu TP Black Tops every night before bed for 7 weeks. My goal is to get to 4 iu daily.
The lathergy forced me to do them at nite before bed.
In the last week, I've uped to to 2.5 iu before bed. So far so good.
I want to follow conventional wisdom and do 2iu early am and then do some fasted cardio. And the remainder 2 iu later in the day.
My only problem is I work til 7 pm four days a week.. I'm in bed SLEEPING by 730 pm.
Additionaly, I go to the gym between 2-3 AM six days a week..
I would have just injected 2iu around 7 pm and my question is when to to take the other 2iu.
My goals are fat loss and new cell muscles.

I'm also running DHB about 400 /week...NPP/300 week.. and test cyp about 400/ week.
Any and all suggestions would be appreciated..
Thanks.
I do think you're overthinking this. If you want to use this protocol, there's no reason why you cannot pin the 2iU in the AM before training even though it's only a few hours later. The rhGH passes through the circulation very, very quickly and its primary action is to increase cIGF-1 from the liver. Timing stuff like this is more relevant for peptides (where it still doesn't matter all that much). Just follow your protocol, titrate up to what you're comfortable with, and let the IGF-1 do its magic.
 

3BILLS

Well-known member
Kilo Klub Member
Registered
Joined
Oct 1, 2007
Messages
1,771
Pin when you go to bed. Pin when you wake up. You sleep at least 5 hours right ?


It's Tricky to rock a rhyme, to rock a rhyme that's right on time
It's Tricky
 

Knight9

Featured Member / Verified Customer / Kilo Klub
Featured Member
Kilo Klub Member
Registered
Verified Customer
Joined
Dec 23, 2006
Messages
9,744
This isn't tricky.

2iu pre bed/2iu upon waking-pre workout
4iu pre bed
4iu pre workout
4iu post workout

These are pretty much all your options.
 

Type-IIx

Active member
Registered
Newbies
Joined
Apr 9, 2021
Messages
160
Here is the time course of circulating blood hGH post-5iU injection (subq- white circles, jet-inject-black dots):

Pharmacodynamics-serum-time-rhGH-subq-vs-jet.png

4.5 hrs+ between subq injections is fine for 5iU subq. Cmax may be reached more quickly with 2iU.

Verhagen, A., Ebels, J. T., Jonkman, J. H. G., & Dogterom, A. A. (1995). Pharmacokinetics and pharmacodynamics of a single dose of recombinant human growth hormone after subcutaneous administration by jet-injection: comparison with conventional needle-injection. European Journal of Clinical Pharmacology, 49(1-2). doi:10.1007/bf00192361
 

Knight9

Featured Member / Verified Customer / Kilo Klub
Featured Member
Kilo Klub Member
Registered
Verified Customer
Joined
Dec 23, 2006
Messages
9,744
Here is the time course of circulating blood hGH post-5iU injection (subq- white circles, jet-inject-black dots):

View attachment 139073

4.5 hrs+ between subq injections is fine for 5iU subq. Cmax may be reached more quickly with 2iU.

Verhagen, A., Ebels, J. T., Jonkman, J. H. G., & Dogterom, A. A. (1995). Pharmacokinetics and pharmacodynamics of a single dose of recombinant human growth hormone after subcutaneous administration by jet-injection: comparison with conventional needle-injection. European Journal of Clinical Pharmacology, 49(1-2). doi:10.1007/bf00192361
This graph is a great illustration of why years ago I was a big fan of slin+gh pre and then slin post as well and made the argument that GH pre and post is micromanagement that is unnecessary. To me...this also shows why GH could be more beneficial pre workout rather than post.


*Humalog 5-10iu pre
*GH 2-5iu pre
Intra workout feeding.
*Humalog 5-10iu post.
Post workout feeding.
 

Type-IIx

Active member
Registered
Newbies
Joined
Apr 9, 2021
Messages
160
This graph is a great illustration of why years ago I was a big fan of slin+gh pre and then slin post as well and made the argument that GH pre and post is micromanagement that is unnecessary. To me...this also shows why GH could be more beneficial pre workout rather than post.
Agreed on all counts.
 

Ak47

New member
Newbies
Joined
Aug 6, 2019
Messages
14
I just pin all of it before going to bed. If lethargy is a problem why risk being less than 100% at work when you can avoid it by just pinning it before bed, waking up refreshed and being energetic at work
 

kilsong

Active member
Registered
Joined
Jun 7, 2012
Messages
570
Thank u all for the suggestions.
Yeah... Definitely over thinking it.
Tomorrow nite I'm gonna just hit 4iu before bed.
Maybe switch it in the future and try 2iu before bed.. Then 2iu post.
 

Knight9

Featured Member / Verified Customer / Kilo Klub
Featured Member
Kilo Klub Member
Registered
Verified Customer
Joined
Dec 23, 2006
Messages
9,744
Thank u all for the suggestions.
Yeah... Definitely over thinking it.
Tomorrow nite I'm gonna just hit 4iu before bed.
Maybe switch it in the future and try 2iu before bed.. Then 2iu post.
I don't know if you are understanding this completely. What are your goals? Are you dieting or trying to get larger?

Larger: One bolus dose.
Leaner: Dose it twice and dose it so the cascade can stimulate fat burning. 2iu pre cardo or pre workout or both if you do them separately.
 

mslmn

Active member
Registered
Verified Customer
Joined
Aug 1, 2006
Messages
397
This graph is a great illustration of why years ago I was a big fan of slin+gh pre and then slin post as well and made the argument that GH pre and post is micromanagement that is unnecessary. To me...this also shows why GH could be more beneficial pre workout rather than post.


*Humalog 5-10iu pre
*GH 2-5iu pre
Intra workout feeding.
*Humalog 5-10iu post.
Post workout feeding.
I agree with you. Now if you had supposedly legit igf-1, where would you fit that in?
 

Matsuo Munefusa

Well-known member
Kilo Klub Member
Registered
Joined
Sep 21, 2010
Messages
3,798
I don't know if you are understanding this completely. What are your goals? Are you dieting or trying to get larger?

Larger: One bolus dose.
Leaner: Dose it twice and dose it so the cascade can stimulate fat burning. 2iu pre cardo or pre workout or both if you do them separately.
You’re overthinking. Just inject the drugs it literally doesn’t matter as long as you don’t go hypo and die from the insulin.

Lethargy is almost always a side beyond 2iu. In that case it’s almost universally agreed on to inject total dose of GH before sleep. This is just common sense. No fuckin chart needed bud
 

beastmode121

Featured Member / Kilo Klub
Featured Member
Kilo Klub Member
Registered
Joined
Jan 23, 2014
Messages
2,310
I pin once; does it make a difference, fuck if I know; my IGF was high pinning only once in the past… so no it doesn’t IMO
 

Type-IIx

Active member
Registered
Newbies
Joined
Apr 9, 2021
Messages
160
I agree with you. Now if you had supposedly legit igf-1, where would you fit that in?
IGF-1 + hGH >> hGH or IGF-1 separately. Administration of both tends to cancel out the negatives of each reciprocal (e.g., hypoglycemia vs. hyperglycemia). People worry too much about timing. If you can afford both, use both and you'll actually get growth (hypertrophy) and lipolysis.
 

Knight9

Featured Member / Verified Customer / Kilo Klub
Featured Member
Kilo Klub Member
Registered
Verified Customer
Joined
Dec 23, 2006
Messages
9,744
You’re overthinking. Just inject the drugs it literally doesn’t matter as long as you don’t go hypo and die from the insulin.

Lethargy is almost always a side beyond 2iu. In that case it’s almost universally agreed on to inject total dose of GH before sleep. This is just common sense. No fuckin chart needed bud
Sorry, if I know a cascade of fat burning and other things happen with a shot of GH and I am trying to burn fat at the most efficient pace, I am going to be injecting GH prior to workout(s) to maximize these events and want it to occur more often than once daily. You guys are calling science 'message board bullshit'. Besides, if you simply look at the graph - you see a large several hour time frame GH is active for and having all those mechanisms occurring during your workout and post workout feeding window(with or without) insulin is what I subscribe to.

In other scenarios, there's no need to get meticulous just do it once a day in a large dose - or 10iu MWF/EOD and be done with it. The only time I would use it pre workout then is if you legit preferred it for whatever reason.

And for you guys running larger doses..if anyone still does that - IMO it does matter if you break your shots up. There are ways 10iu can go further spread over shots than in one bolus dose..and vice versa.
 

Knight9

Featured Member / Verified Customer / Kilo Klub
Featured Member
Kilo Klub Member
Registered
Verified Customer
Joined
Dec 23, 2006
Messages
9,744
I agree with you. Now if you had supposedly legit igf-1, where would you fit that in?
I'll defer to someone else here as I don't and won't use IGF-1. In the past, I considered Des and Mgf.
 

Staff online

  • Big A
    IFBB PRO/NPC JUDGE/Administrator

Forum statistics

Total page views
512,518,223
Threads
125,878
Messages
2,462,230
Members
156,446
Latest member
ape1nope
Top