- Joined
- Mar 6, 2009
- Messages
- 26,311
I love finding studies like this. There is so much misinformation posted on forums about AAS.
**broken link removed**
Liver disease. AAS also have a role in treating patients with hepatitis-related malnutrition. In a study of 271 patients with alcoholic hepatitis, oxandrolone along with a high calorie supplement was compared with placebo and a low calorie supplement. Significant improvement in liver function and overall survival was observed in the oxandrolone and high calorie supplement group (52). Similarly, oxandrolone therapy has been shown to result in a reduction in 6-month mortality in patients with alcoholic hepatitis (53). In a V.A. cooperative study of 273 patients with moderate protein calorie malnutrition secondary to alcoholic hepatitis, 80 mg/d oxandrolone along with an enteral food supplement resulted in improved 6-month survival, decrease in liver injury, and improvement in malnutrition compared with the placebo group (54). However, no significant improvement was observed in patients with severe malnutrition. Although this dose of oxandrolone was very high, especially in a population with established liver disease, no hepatotoxicity was reported in subjects taking oxandrolone.
**broken link removed**
Liver disease. AAS also have a role in treating patients with hepatitis-related malnutrition. In a study of 271 patients with alcoholic hepatitis, oxandrolone along with a high calorie supplement was compared with placebo and a low calorie supplement. Significant improvement in liver function and overall survival was observed in the oxandrolone and high calorie supplement group (52). Similarly, oxandrolone therapy has been shown to result in a reduction in 6-month mortality in patients with alcoholic hepatitis (53). In a V.A. cooperative study of 273 patients with moderate protein calorie malnutrition secondary to alcoholic hepatitis, 80 mg/d oxandrolone along with an enteral food supplement resulted in improved 6-month survival, decrease in liver injury, and improvement in malnutrition compared with the placebo group (54). However, no significant improvement was observed in patients with severe malnutrition. Although this dose of oxandrolone was very high, especially in a population with established liver disease, no hepatotoxicity was reported in subjects taking oxandrolone.