Man, it was big 15 years ago. I was actually thinking about it yesterday. Be interesting to see the responses hereCame across this looking at research, however, couldn't find anything on the product. Anyone used it, or logged it?
Always my feeling on it..everyone was trying to find a new game changer like igf1..didn’t pan out imhoComplete was of money.
My sentiment exactly. Same with “Delta Sleep Inducing Peptide” (DSIP). Started out as a big thing and then just fizzled out.Back in the Dat days, MGF was the rageee. People were experimenting with everything. I personally stuck to GHRP 2 + Mod GRF combo .
But people were into MGF. I feel like peps have realllly cooled down the past 4-5 years. In the 2010's, it was the wild west of people trying shit to see what they could get away with. But i rarely hear of anything new or interesting now.
The issue is that MGF causes growth via myogenesis (regeneration) rather than hypertrophy (remodeling) pathways, so it's collagen and fibrotic tissue deposition. You see MGF increased with high volume exercise only in elderly subjects (regeneration pathways, aching to injury). The growth that occurs is not in contractile elements (myofibrils).I used MGF with IGF-DES for a cycle in my right arm only. My goal was to bring up my right arm because it was significantly smaller from a nerve injury that caused loss of function of my right tricep.
I can say that after the month cycle of MGF and IGF-DES, my right arm made more progress in becoming symmetrical to my left than any previous month. Thats just my personal experience with it.
This. First it was creatine, then myostation blockers, then lr3, beta alanine was in there for a while, then peptides, then SARMs, whatever fills pockets will be the next big thing.Complete was of money.
Sounds like it might be good to inject into injured areas, like a bad shoulderThe issue is that MGF causes growth via myogenesis (regeneration) rather than hypertrophy (remodeling) pathways, so it's collagen and fibrotic tissue deposition. You see MGF increased with high volume exercise only in elderly subjects (regeneration pathways, aching to injury). The growth that occurs is not in contractile elements (myofibrils).
This is not clearly stated in the literature, but my own inference from looking through it.
I thought this figure would help people understand your post.Satellite cells are really a spectrum of cells with varying degrees of differentiation into myo-specific cells, varying from "pure" stem cells, to something myostemish, to activated myoblasts.
MGF only works on differentiated myoblasts which are already active, whereas most satellite cells are not active. Then there is the issue that the MGF receptor seems to be intercellular and nuclear, which makes it hard to reach with something the size of a protein. FGF and HGF reaches a greater variety of the satellite cells, and HGF can activate the cells with motility.
These are mitogens. That's what we're doing with MGF, proliferating cells, not simply the anabolism of fibers.
My understanding is DSIP ONLY works via intravenous injection I wasn't willing to go this route to try itMy sentiment exactly. Same with “Delta Sleep Inducing Peptide” (DSIP). Started out as a big thing and then just fizzled out.