- Joined
- Jan 15, 2012
- Messages
- 2,594
Was doing some digging into high doses metformin and came across all these studies indicating doses of 2500mg to 3000mg provide benefits over lower doses, when given to normal sized people and females. I wonder if bodybuilders with much bigger size could benefit from the same doses or even higher. It seems most guys on here limit themselves to around 1gram per day.
High-dose metformin safe, effective in Japanese adults with type 2 diabetes
In Japanese adults with poorly controlled type 2 diabetes, high doses of metformin administered twice or three times daily improved fasting plasma glucose and 24-hour glycemic profile in a dose-dependent fashion, according to findings reported in the Journal of Diabetes Investigation.“While the...
www.healio.com
Effects of High- and Medium-Dose Metformin Therapy on Cardiovascular Risk Factors in Patients With Type II Diabetes
OBJECTIVE. To study the dose response to metformin in type II diabetic patients.RESEARCH DESIGN AND METHODS. Type II diabetic patients with a BMI > 25 were t
diabetesjournals.org