2-4 HGH IUs a day- difference and realistic expectations?

[OldManLogan]

What can someone expect, given solid T numbers at the top of normal range/ optimal range expect out of daily 2 IUs of HGH over time?
And what about 4, beyond a replacement dose, what is realistic? Fat loss? Anabolism? Better skin/recovery/ joint repair..?

 

[Jefe]

I started about 9 months ago for my shoulder surgery and weight loss. 2iu am/pm.

Fat loss noticed right away. Body comp changes started around month 8.

 

[thehogsters]

It's definitely a slow marathon. I have done 3 runs of hgh. Eight months twice and thirteen months last time. I played around with dossage but usually stuck to 4iu every morning. I did notice after a month I was able to gataway with more cheat meals without consequences. Definitely had the best physice of my life.

 

[Steve123]

What can someone expect, given solid T numbers at the top of normal range/ optimal range expect out of daily 2 IUs of HGH over time?
And what about 4, beyond a replacement dose, what is realistic? Fat loss? Anabolism? Better skin/recovery/ joint repair..?

For me it just takes a while. I didn't really start to notice anything until around 12 weeks or so. It doesn't punch you in the face. It just kind of sneaks up on you. I found after about 12 weeks I generally had a better sense of well being, more positive, definitely noticed some subtle skin improvements, fat loss. Just stay consistent and disciplined with it. Depending on your goals, more is not always better.

 

[sciroxx-lab]

Just my two cents—when it comes to HGH, unlike steroids where more isn't always better, there is a clear long-term advantage with slightly higher doses, particularly within the lower range of 2–4 IU. For example, this article -HGH and anti-aging- highlights a clinically proven anti-aging protocol using a dosage of 0.015 mg per kg of HGH, which equates to 4.5 IU for a 100 kg (220 lbs) individual, and for a reason.

 

[gungalunga]

Expect improvements, not miracles. With just about anything we use....your results will be good as long as your diet and training are on point.

 

[MackCoach]

2 units? Healthy but barely noticeable
4 units … start getting leaner and it’s noticeable within a few weeks …. Mild muscle size add on I see it in delts and traps
6 units + now we really notice the lean hard look plus muscle gain starts to pop

It’s not months until you notice results

GH starts working immediately

Results are within 2 weeks

I think a lot of guys say that you have to run a long-term just because of the fact that you can run it long-term. It does not mean that you have to run it for a long time before you notice anything at least that has been my experience.

 

[OldManLogan]

2 units? Healthy but barely noticeable
4 units … start getting leaner and it’s noticeable within a few weeks …. Mild muscle size add on I see it in delts and traps
6 units + now we really notice the lean hard look plus muscle gain starts to pop

It’s not months until you notice results

GH starts working immediately

Results are within 2 weeks

I think a lot of guys say that you have to run a long-term just because of the fact that you can run it long-term. It does not mean that you have to run it for a long time before you notice anything at least that has been my experience.

This is assuming diet, exercise and some basic leanness (12% or so bodyfat) is in place and T levels are optimal (800-1000 Total, free t 15% or more) correct?

 

[hemipower]

2iu is ideal for long term anti aging use and budget reasons, continuous year round ...
3iu is best bang for the buck (sweet spot) daily preferably split into two pins of 1.5iu am/pm
4iu does not seem much better than the returns at 3iu
5-10iu personally... too sleepy and swollen to be able to endure for long... I'd think these larger doses would be better pulsed... day on day off... training days only maybe...

I tend to "blast and cruise" here also. Much of the year at 2iu cruising, ramp up to 3-4iu for a couple months here and there. A couple months a year on MK677 or peptides.

 

[Steve123]

Just my two cents—when it comes to HGH, unlike steroids where more isn't always better, there is a clear long-term advantage with slightly higher doses, particularly within the lower range of 2–4 IU. For example, this article -HGH and anti-aging- highlights a clinically proven anti-aging protocol using a dosage of 0.015 mg per kg of HGH, which equates to 4.5 IU for a 100 kg (220 lbs) individual, and for a reason.

2iu is ideal for long term anti aging use and budget reasons, continuous year round ...
3iu is best bang for the buck (sweet spot) daily preferably split into two pins of 1.5iu am/pm
4iu does not seem much better than the returns at 3iu
5-10iu personally... too sleepy and swollen to be able to endure for long... I'd think these larger doses would be better pulsed... day on day off... training days only maybe...

I tend to "blast and cruise" here also. Much of the year at 2iu cruising, ramp up to 3-4iu for a couple months here and there. A couple months a year on MK677 or peptides.

I just started back up on 3iu and have been sleepy. I can't imagine running 10.

​

 

[hemipower]

I just started back up on 3iu and have been sleepy. I can't imagine running 10.

​

To be honest I peaked at 8iu rips back in the day and I gained like 10 lbs of mainly water weight in 2 weeks... and was so tired I would fall asleep repeatedly during the day... sitting at my desk too long and pass out... it nearly happened in traffic one day and that was my final day at 8iu lol. I have not exceeded 4/day since.

The below study combines gh therapy with metformin, vit D, zinc and DHEA and the results are amazing... essentially a 2.5 year aging reversal in a year... they used 0.015mg/kg so a 100kg bodybuilder would need 1.5mg or 4.5iu - they did 4 nights a week though. Of course other markers improved as well (lean mass etc).

I am considering bumping back to 3-4iu and doing 5 days a week... taken at night. I have done 2iu every morning for most of the last year or so without "blasting" to save a few bucks.

Reversal of epigenetic aging and immunosenescent trends in humans - PMC

Epigenetic “clocks” can now surpass chronological age in accuracy for estimating biological age. Here, we use four such age estimators to show that epigenetic aging can be reversed in humans. Using a protocol intended to regenerate the thymus, we ...

pmc.ncbi.nlm.nih.gov

 

[BBSQ5]

Just catching up on this at the right time.

So, I started back in 3iu’s of Somatropin cartridges this week. Of course if Katy is correct, it states that the 1mg/day is truly best bang for buck long term daily dose.

Was going to run all the time at this, but basically staying 3 days on, 2 days off for the little bit of hand issues I get with it and this helps.

Never been one to run too high, because it really messes with me water retention wise and hand wise.

 

[Jacked_]

Do any of you guys have igf-1 scores on 2-4iu? I would be very curious to see.

 

[BBSQ5]

Do any of you guys have igf-1 scores on 2-4iu? I would be very curious to see.

I do NOT have any yet, which obviously does not help you. But, I will after about 12 weeks at the 3iu’s and hope that it at least puts my IGF at the top of the scale on Labcorp, because I’ve never been able to get it away from the middle with the peptides or MK-677. All reputable and tested sponsors, so maybe I just haven’t taken high enough doses of that stuff.

 

[Jacked_]

I do NOT have any yet, which obviously does not help you. But, I will after about 12 weeks at the 3iu’s and hope that it at least puts my IGF at the top of the scale on Labcorp, because I’ve never been able to get it away from the middle with the peptides or MK-677. All reputable and tested sponsors, so maybe I just haven’t taken high enough doses of that stuff.

Any of the secretagogues don’t even hold a candle to 2iu of gh. It’s actually probably cheaper to run a good generic than any of the ghrps I’d think at 3iu. I would think a 350 igf could be a reasonable expectation.

 

[SwedishSteel]

It's definitely a slow marathon. I have done 3 runs of hgh. Eight months twice and thirteen months last time. I played around with dossage but usually stuck to 4iu every morning. I did notice after a month I was able to gataway with more cheat meals without consequences. Definitely had the best physice of my life.

No better recovery, mental clarity, better skin - even with so long runs?

 

[OldManLogan]

Any of the secretagogues don’t even hold a candle to 2iu of gh. It’s actually probably cheaper to run a good generic than any of the ghrps I’d think at 3iu. I would think a 350 igf could be a reasonable expectation.

100% my experience. I’ve run cjc /ipa, tesa/ipa for 12-16 weeks each, and resultswise- it’s not even close in cost and effectiveness compared to 3 IUs GH.
Not even close.
Maaaaybe Tesa for the visceral fat targeting it was designed for, and that’s a maybe.

 

[joeirock]

agree with most here ..
in my experiance the results start to get noticed within a week or two .. definitly start getting a bit leaner .. muscles fuller .. etc .. i have never done just 2iu/day .. but if i did i would do it b4 bed IM .. you get more out of the GH while youre sleeping ... and its active into the morning for some fasted cardio..etc ..
i used to take 4iu b4 bed every night .. for as long as i can keep buying GH i will do at least that ..
i added in 2iu upon waking and noticed a bit more
currently
i take 4iu b4 bed and then 2iu upon waking and 2iu pre or post workout depending on days schedule .. just adding the 2 iu pre post workout that i wasn't doing b4 i noticed a bit of a difference in how much i can eat without putting on fat..

 

[BBSQ5]

Any of the secretagogues don’t even hold a candle to 2iu of gh. It’s actually probably cheaper to run a good generic than any of the ghrps I’d think at 3iu. I would think a 350 igf could be a reasonable expectation.

Yeah, I wasted so much needless $$ on all of those things, when I should have just been using 3iu’s per day of my Somatropin. Lesson learned and will not be wasting $$ on that crap anymore.

 

[Tiny Too]

Do any of you guys have igf-1 scores on 2-4iu? I would be very curious to see.

This was running blacktops at 8 shots per vial. So it should be right around 2iu factoring 16/vial. 428 igf1

This was fasted blood draw at 7:15am. Growth was pinned the night before probably around 10pm. Not sure if it was IM, probably subQ in stomach.

I was running GH pretty much daily.

E2 was in the gutter, but doc didn’t order a sensitive test, just the basic assay. I have no idea how accurate the 10.9 estradiol actually is.