A Solution to Tren- Understanding Histamine and how to regulate it

[svenrpb]

If unchecked for long enough it is possible as with excess histamine and irritated mast cells your body and respiratory will be in an inflamed state.

Overall I’d check deeper into your blood work and immune markers though on that one personally. There’s still a root cause under histamine issues- in this case it’s Tren or increased androgens. In other cases it’s eating food high in histamines.

When it´s tren or other androgens and DAO/anti histamine doesn´t fix it, the only option is to go to cruise/low AAS ro reduce histamine inflamation?

 

[bbxtreme]

When it´s tren or other androgens and DAO/anti histamine doesn´t fix it, the only option is to go to cruise/low AAS ro reduce histamine inflamation?

That’s what I would do unless I was in a prep, in that case I’d suffer through it (just being honest).

Mast cells are found in every cell of the body so it affects many aspects when they’re irritated and excess histamine releases that can’t be metabolized. In most cases though the above items I suggested will restore balance, but isn’t a root cause fix. Just mitigation of side effects to keep further damage from happening.

The other thing to note is that you’ll be able to manage it better if you’re cutting while on tren as you’ll be in a deficit and lower inflammation levels which will allow your body to be more resilient.

 

[Bodyofwork365]

Slightly off topic but would these histamine blends also help alleviate some of the side effects of viagra? If I could get a double whammy effect and mitigate tren and viagra sides in one shot that would be huge!

 

[bbxtreme]

Slightly off topic but would these histamine blends also help alleviate some of the side effects of viagra? If I could get a double whammy effect and mitigate tren and viagra sides in one shot that would be huge!

You want less sex?

Kidding, but Viagra and Cialis inhibit mast cells’ degranulation. Meaning they could alleviate many of the respiratory issues from Tren. Source below.

I would try moving to Cialis and keeping the dose around 2.5mg to 5mg daily instead of using higher dosages as needed.

Often times the symptoms may be worst or happen as a byproduct of high androgens and being on items such as Tren so is a possibility it could help alleviate some issues as a second hand effect.

Anti- Allergic Effect of Sildenafil and Tadalafil in Ovalbumin Induced Bronchial Asthma in Rats

Anti- Allergic Effect of Sildenafil and Tadalafil in Ovalbumin Induced Bronchial Asthma in Rats. PubMed, SCI, Scopus, ESCI, PMC indexed

www.fortunejournals.com

 

[bbxtreme]

Great read! I still love tren and I'd love to use it again.

What I hate (and love) is that I get zero sides from Tren (ok...to be fair haven't taken it since 2018). But I was on it off and on for years at a lower dose of 100-150mgs a week and I sleep fine, feel fine, etc. I am just so damn paranoid about kidney damage from it from mechanisms unrelated to BP as my BP is under control.

Very valid concern if used at high amounts for long periods of time.

I don’t run tren without:

2g astragalus daily
1g Chanca piedra daily
4g taurine daily

This is strictly for renal protection.

 

[Stewie]

Slightly off topic but would these histamine blends also help alleviate some of the side effects of viagra? If I could get a double whammy effect and mitigate tren and viagra sides in one shot that would be huge!

DAO isn't the player with nasal congestion from PDE5i. eNO (vasodilation) is believed to be the culprit.

 

[Stewie]

DAOi isn't the player with nasal congestion from PDE5i. eNO (vasodilation) is believed to be the culprit.

 

[Flex500]

Very valid concern if used at high amounts for long periods of time.

I don’t run tren without:

2g astragalus daily
1g Chanca piedra daily
4g taurine daily

This is strictly for renal protection.

thanks!

 

[juggy38]

DAO isn't the player with nasal congestion from PDE5i. eNO (vasodilation) is believed to be the culprit.

Viagra for me is much much worse than cialis.

 

[heavyhitter]

I see diphenhydramine is not mentioned in the PDF. Given that it's the most widely used anti-histamine why doesn't it work here?

It’s weak. Zyrtec is a better histamine blocker for this

 

[hevi-head]

Heart burn, GERD, insomnia, digestive issues, brain fog, respiratory issues, etc.

Are night sweats related to the histamines at all? That’s probably the worst noticeable side I get. No insomnia or GERD really to speak of

 

[heavyhitter]

This is one of many articles I have written for my brand. Given our focus is “natural solutions” I typically aim to only discuss natural solutions in our articles.

For someone looking to mitigate the side effects of tren one could use an OTC anti-histamine with DAO to achieve a similar if not the same result.

The goal is to metabolize the excess histamine (DAO does this) while managing the mast cells so balance is restored which will alleviate the side effects.

Maybe one day I’ll have enough time to write articles fully dedicated to bodybuilding. Lol

Question also inhibits histamine. I would throw in Zyrtec as well with the dao. Also famotadine.
And just for clarification to show I know what I’m talking about….u have mast cell activation disorder

 

[Doitagain]

DAO isn't the player with nasal congestion from PDE5i. eNO (vasodilation) is believed to be the culprit.

In a study on subjects using Sildenafil, the rhinoscopy showed a characteristic increase of the volume of the inferior turbinates . Nitric oxide is present in the nasal mucosa and is responsible for vasodilation, causing congestion and nasal obstruction.

 

[bbxtreme]

Question also inhibits histamine. I would throw in Zyrtec as well with the dao. Also famotadine.
And just for clarification to show I know what I’m talking about….u have mast cell activation disorder.

From high levels of androgens used over long periods of time, yes.

I personally am not a fan of using OTC acid blockers like famotadine. They’re just masking issues. Instead I use mastic gum, aloe, zinc carnisine and slippery elm as my morning regimen.

Mast cells being pissed off will absolutely cause night sweats. DAO is more for histamine metabolism so you’d want to use the other items mentioned in my article to cover the mast cell regulation- holy basil, stinging nettle and quercetin.

 

[aDw32]

Recently said to myself - last attempt.

25 mg e2d (not kidding)

After 4st shot, had to stop. Gut said BIG NO. Already after second shot (25 mg to remind) felt bubbling in my stomach all day long. After 4th, pure pain.. (fuck, things never happened when i was young )

But now it seems it wasn't that last attempt i thought thx @bbxtreme, i'm definitely gonna try and give it last chance

 

[Flex500]

Recently said to myself - last attempt.

25 mg e2d (not kidding)

After 4st shot, had to stop. Gut said BIG NO. Already after second shot (25 mg to remind) felt bubbling in my stomach all day long. After 4th, pure pain.. (fuck, things never happened when i was young )

But now it seems it wasn't that last attempt i thought thx @bbxtreme, i'm definitely gonna try and give it last chance

nothing wrong with 25mgs EOD. I loved that!

 

[bbxtreme]

Recently said to myself - last attempt.

25 mg e2d (not kidding)

After 4st shot, had to stop. Gut said BIG NO. Already after second shot (25 mg to remind) felt bubbling in my stomach all day long. After 4th, pure pain.. (fuck, things never happened when i was young )

But now it seems it wasn't that last attempt i thought thx @bbxtreme, i'm definitely gonna try and give it last chance

Add in the things I mentioned and you should alleviate those issues.

 

[Sectør]

I find the tren sides very manageable with a low test, high tren combo (test from 250mg/week to 375/week) with 700 tren/week

If i start going up in test dosage or add in other aromatizing compounds, the tren sides seem to drastically increase, maybe due to an increase in estrogen and/or prolactin (which scales with estrogen)

 

[bbxtreme]

I find the tren sides very manageable with a low test, high tren combo (test from 250mg/week to 375/week) with 700 tren/week

If i start going up in test dosage or add in other aromatizing compounds, the tren sides seem to drastically increase, maybe due to an increase in estrogen and/or prolactin (which scales with estrogen)

They’re both androgenic. Dropping Test will help mitigate some of this, but that’s not nearly as fun as high test and moderate Tren.

 

[totalrecomp]

It’s weak. Zyrtec is a better histamine blocker for this

Zyrtec or claritin are also NOT linked to increased risk of dementia. Once in a while diphen is no big deal but I would never rec. taking daily, even for 8-12 weeks, much better options.