jeroendebleser said:
"Perhaps a stupid question and certainly not meant to diss you but if it works so well for you, why do you only take it for a half year and not the entire year?"
That is a very good question. The reasons I only use it for 6 to 7 months total, is because by the 7th month I noticed from my bloodwork that the peak level (+100 added IGF-1 points above baseline during months 1 thru 6) would begin to fall a bit (ie only +95 points increase). This was seen each year at the 7th to 8th month. By the 8th month it was around (+80 point increase). I also studied the MK677 studies and found the same thing was happening with the others in the study. The peak level which was held for at least 6 months began to decline a bit. This told me it was best to take a break from it at that time, then get back on it again later...similar to a steroid cycle is how I use it then. There is a slight withdrawal when coming off it after 7 months, but nothing major--just some tiredness for several days, a day or so of lower spirits, and then I was back to my normal happy self after around 5 days.
Self:
227 igf-1---->372 igf1 (25mg mk677) = increase of 145 points for 1st two weeks
Self:
227 igf-1---->327 igf1 (25mg mk677) = increase of 100 points after the 1st couple weeks and remains so for 6 months. A regulatory system is kicked in by the body
after the first 2 weeks to keep the levels from rising too high.
7 months in while taking it, I had labs done, mk677 had no detrimental effects on my insulin, glucose, A1c, etc.
Labs from Sept 26, 2018:
Insulin 8.2 uU/ml , normal, low =2.6, high = 24.9
Glucose: 89.0 mg/dl, normal, low = 70, high = 99
HbA1c: 5.1%, normal, low = 4.0, high = 5.6
Also noticed: enhanced exercise tolerance in the gym and on treadmill aside from the other effects listed above.
More detail:
IGF-1 range for my age group of 48 ------- 67 to 205 ng/ml igf-1
IGF-1 range for older adults ----------------- 59 to 225 ng/ml igf-1
IGF-1 range for young adults is ------------ 116 to 358 ng/ml igf-1
4-6-18, baseline igf -1 = 227 ng/ml------------------------------------------------- baseline
4-11-18, 2 days on 4iu of Chinese pharm grade HGH = 380 ng/ml---------increase of 153 points
4-25-18, 2 weeks on mk677 only = 372 ng/ml------------------------------------increase of 145 points (nearly 150 point increase only lasts 2 weeks)
9-7-18, 6 months on mk677 only = 322 ng/ml------------------------------------increase of 95 points
11-2-18, 8 months on mk677 only = 304 ng/ml-----------------------------------increase of 75 points (levels start to fall after 6 months on mk677)
-----------------------------------------------------------------------------------------------------------------------------
new year:
3-18-19, 4 weeks on mk677 only = 327 ng/ml-------------------------------------increase of 100 points, (2-22-19 thru 3-18-19 thus far)
Year 2018 = 322 ng/ml igf-1 (average level during 1st 6 months on 25mg mk677 in morning) is equivalent of 3.4 iu pharm grade GH from China, as 95 point raise per each 1iu of hgh for me.
Year 2019 = 327 ng/ml igf-1 (after 1 month on 25mg mk677 in the am) is equivalent to 3.4 iu pharm grade GH from China, as 95 point raise per each 1iu of hgh
for me.
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