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Genuine E2 Question

Papabigbiceps

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Sep 17, 2022
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I can't seem to nail down exactly what I should expect or what signs that my E2 has crashed or is crashing/low. Trying to look on google shows me so many possibles that it looks like so many other ailments. Wondering if someone could give me an anecdotal of what they expirenced or knows what typical signs would be.
 
I can't seem to nail down exactly what I should expect or what signs that my E2 has crashed or is crashing/low. Trying to look on google shows me so many possibles that it looks like so many other ailments. Wondering if someone could give me an anecdotal of what they expirenced or knows what typical signs would be.
Why don't you just get bloodwork. A lot of high and low e2 symptoms overlap. It's $69 at labcorp. If you can afford gear, you can afford to get blood drawn.

 
Why don't you just get bloodwork. A lot of high and low e2 symptoms overlap. It's $69 at labcorp. If you can afford gear, you can afford to get blood drawn.

I will if I have actual concern it's low. Just trying to see if I can find some constants between anyone who has expirenced it. I'm running 500eq/600testC, but I'm only 2 weeks in. Maybe the test is high enough to not be a concern? Just trying to look ahead.
 
I will if I have actual concern it's low. Just trying to see if I can find some constants between anyone who has expirenced it. I'm running 500eq/600testC, but I'm only 2 weeks in. Maybe the test is high enough to not be a concern? Just trying to look ahead.
It's going to be a guessing game and highly individualistic, besides you should be getting bloodwork regularly anyways. How else are you going to dial in your estrogen? I don't understand the head in the sand approach. I'll leave it there as who am I to lecture you... just know that i'm genuinely trying to help. Anything other than bloodwork is just a guess and in my opinion that just doesn't cut it.
 
It's going to be a guessing game and highly individualistic, besides you should be getting bloodwork regularly anyways. How else are you going to dial in your estrogen? I don't understand the head in the sand approach. I'll leave it there as who am I to lecture you... know that i'm just trying to help.
It's less of head in the sand and more of me venturing into my own understsanding. Don't see it a lecturing, but also don't be a dick about it. Just trying to learn exactly how to do this right. Last time I had someone holding my hand through it and just kind of listened to instruction. I will do routine bloods probably at week 3 or 4, and I got a baseline test/t3 panel with my Metabolic through my primary care.
 
It's less of head in the sand and more of me venturing into my own understsanding. Don't see it a lecturing, but also don't be a dick about it. Just trying to learn exactly how to do this right. Last time I had someone holding my hand through it and just kind of listened to instruction. I will do routine bloods probably at week 3 or 4, and I got a baseline test/t3 panel with my Metabolic through my primary care.
Don't be a dick? lol what? Ok have fun with your guessing game. What a fucking idiot.

Hey guys, can someone let me know what it feels like to have high blood pressure? I'll get it tested after I know the symptoms. 🤣
 
Hmmm, maybe we have a miscommunication. I said I don't see it as lecturing, and don't want you to either. But asked you not to do exactly what you did.
 
Don't be a dick? lol what? Ok have fun with your guessing game. What a fucking idiot.

Hey guys, can someone let me know what it feels like to have high blood pressure? I'll get it tested after I know the symptoms. 🤣
Hmmm, maybe we have a miscommunication. I said I don't see it as lecturing, and don't want you to either. But asked you not to do exactly what you did.
Yeah so maybe chill a little. I'm actually trying to learn but didn't want you to go in on me.
 
I'm not sure why, but I wasn't super thrilled the Hyperemia was the first to respond. This person seems to get into pissing matches on here.
 
You need to get the sensitive test to check e1,e2 and total.

EQ can crash E2 and elevate E1 depending on polymorphisms.

Low E2 for me….knees hurt, extreme anxiety and lethargy. BP labile
 
You need to get the sensitive test to check e1,e2 and total.

EQ can crash E2 and elevate E1 depending on polymorphisms.

Low E2 for me….knees hurt, extreme anxiety and lethargy. BP labile
Thank you. Seems like joint pain, and lethargy are faily common. I will get bloods, any recommendation as to how soon? Only on week 2.
 
I can't seem to nail down exactly what I should expect or what signs that my E2 has crashed or is crashing/low. Trying to look on google shows me so many possibles that it looks like so many other ailments. Wondering if someone could give me an anecdotal of what they expirenced or knows what typical signs would be.
You don't need E1 blood test just go for E2.
Going with sensations won't help you nailing the correct values of E2, which has to stay in range... Usually <51pg/ml

If you can ask for Ultra sensitive blood test, but even the usual ECLIA will be enough.

A common ratio Test:EQ Is 1:0,8 try to go for that, so add more Test or lower EQ.
 
You don't need E1 blood test just go for E2.
Going with sensations won't help you nailing the correct values of E2, which has to stay in range... Usually <51pg/ml

If you can ask for Ultra sensitive blood test, but even the usual ECLIA will be enough.
Informative! Thank you, that would have been another question, as far as what range it should be. I'm not trying to be dependant on sensations, but looking for early warning signs. I realize bloodwork is the only way to actually tell.
 
Informative! Thank you, that would have been another question, as far as what range it should be. I'm not trying to be dependant on sensations, but looking for early warning signs. I realize bloodwork is the only way to actually tell.
Exactly.... Signs are pretty much similar but just get used to do E2 blood test, it's the best way to use steroids successfully.

Also remember to check your healthy blood markers for hematocrit/hemoglobin, kidneys so you will know if steroids will raise those values which are important for your health.
 
I'm not trying to be dependant on sensations, but looking for early warning signs.
I've only had low e2 once and that was from way too much arimidex. When it starts to get too high, my sex drive will not be as strong, some nipple sensitivity, and feeling slightly lethargic. That's when I'll get e2 checked with bloodwork
 
I can't tell the difference with E2 at 13 or at 108. feels the same to me. I just go by blood worth.
 
Ultalabs is your friend man. I feel mentally better with my e2 a little above normal but for health reasons I won’t let it get to high
 
Here are my low e2 and high e2 symptoms. I pay very close attention to how I feel and very closely monitor my mental health, so I feel pretty confident with the explanations below. Also, historically I have tried countless times to dose an AI based on a predicted schedule of when I "should" need it, and I almost always ended up in low e2 territory. You will see that a lot of advise from people says to "monitor how you feel and when you know your e2 is high, you take an AI". I find that advice to be the most appropriate for me. I don't have endless money and time and schedule flexibility to just keep going to get an ultra-sensitive e2 test every 2 weeks.

Slightly/moderately low E2 symptoms:

1. I get more laser focused at work and I am able to concentrate on discrete tasks better. I don't laugh as often and jokes are more difficult to find funny. I am more serious and people are likely to ask me why I look so serious or angry. I can sustain my concentration better.
2. I wake up with more frequent and stiffer morning erections. In the past I have chased this as a metric, but I have learned this is not super valuable information to me as far as how well my actual sexual performance will go.
3. My elbows and knees may start to have some stiffness and I'll definitely be more aware of my joints during a workout
4. Thoughts will start to enter my mind that don't usually, and they are usually trending negative. Whatever problem is going on with me (particular if I'm in a relationship), my mind will find a reason to focus on that and see the bad outcomes or feel anger and resentment towards it.
5. I'll drop a lot of water and find myself peeing a lot more frequently. Visually I'll look dramatically better than I did a few days ago, because I'm suddenly very dry. I see veins on my abs more prominently. I look at myself and think "see why can't I look like this all the time? this is the way I'm supposed to look."
6. My appetite tends to go down
7. My workout endurance goes down and I find that I'm not as strong on max effort sets
8. I don't sleep as long
9. I'll have more acne that appears in the usual cystic acne spots (around my neck/shoulders/back/hips/chest)

Very/extremely low E2 symptoms:

1. Don't ever get to this point. If you experience the slightly/moderately low E2 symptoms, and you take more aromatase inhibitor before those symptoms have reversed course, you are going to regret it.
2. My mental health is the worst it's ever been. I hate everyone, even the love of my life. I can't stop the stream of unending bad outcomes and terrible bitterness or anger and resentment that has appeared out of nowhere about literally everything that bothers me.
3. I can't stay awake at all, but not because I'm lethargic (like a high e2 symptoms); rather, I can't stay awake because I feel physically exhausted by simply keeping my eyes open. Like I've run a marathon on 3 hours of sleep and 10 cups of coffee and no food. When I take anything with a stimulant, it doesn't work. At all.
4. My dick doesn't work entirely. Unlike the high e2 symptom where it becomes less hard during sex but generally still works, this is something else entirely. I've literally had a woman who I found very attractive give me oral for 15 minutes and my dick stayed small and flaccid. And I was filled with all sorts of unhealthy emotions when that happened because as you can imagine, I wanted it to work, but didn't understand why.
5. Furthermore, if you are extremely low E2, even taking Cialis or Viagra won't do anything. You need some estrogen for your dick to function, and if it's crushed, no amount of PDE-5 inhibitor will save you. Learned that one the hard way too.
6. You have almost no workout endurance at all. We're talking like, one hard set and you're done. You won't even want to train.
7. You will be peeing constantly and each time you feel like you have to piss, barely any liquid will come out.
8. Joints that you forget you have will start to hurt and pop, including your toes, the heels of your foot, and your hips and sacroiliac area. You will be very aware of your spine during all lifts and you may have generalized low back pain from simply sitting down.
9. I'll look in the mirror and look very small, and generally be disgusted with how I look, even though I am the driest I have ever looked. I will not be happy in any way/shape/form with anything regarding my appearance.
10. I'll have no new acne that appears

---

Slightly/moderately high E2 symptoms:

1. I'll start getting more acne in the usual spots, but it's usually not cystic.
2. My face will look slightly more oily
3. My body will appear like I gained more bodyfat rather suddenly, and my stomach will appear like I'm bloated for a very long time after I've eaten anything. Even when I wake up in the morning, I'm very aware of how fat my face and neck look, and it makes me question whether or not I'm truly eating like garbage.
4. I generally feel mentally pretty good. I don't really focus hard at work, but I tend to enjoy my life outside of work a lot more. I enjoy playing with pets more, and I am much more forgiving when shit goes wrong or things happen unexpectedly. I am more calm and more patient.
5. I'm feeling pretty lethargic and feel like I could have slept about 4 more hours after I got enough sleep. Coffee still works, but I need more of it than usual.
6. My dick still works, and during sex, it feels great, but I tend to finish faster than usual.
7. Really, overall, the main tells that I am at this point and I don't want to increase it further are the water retention and lethargic symptoms I describe in #3 and #5. Once these bother me enough, I'll take the smallest dose of AI I have and wait.

Very/extremely high E2 symptoms:

Everything described in the slightly/moderately list of symptoms, PLUS the following:

1. I have a high likelihood of crying during a sad movie, or when I think about my parents, or contemplate being alone. I feel like crying is a possibility during most things, and can't understand why I can't keep it together.
2. I have a very high likelihood of being triggered in my relationship by what my partner does, which will lead to feelings of jealously, irrational anger, rumination, and projecting things that my partner is thinking, when she isn't.
3. I don't feel like I have any self-confidence, and feel very needy and clingy with my partner, in a negative way. For example, during this time, the thought of my partner going off to hang out with her friends alone terrifies me. I get a range of thoughts such as "does she hate me? is she going to cheat on me? why do I always put her needs before mine when she doesn't do the same for me? why doesn't she love me the way i love her?"
4. My dick will still work, but unlike the low e2 symptoms, I don't have any sexual desire. It's sort of the inverse of the low e2 dick problem. In the low e2 scenario, I have a ton of mental desire for sex, but my dick WILL NOT move. In the high e2 scenario, I have very little if any sexual desire, but my dick could become hard if it was mechanically stimulated and/or I took Cialis and got oral. It just wouldn't be as hard as it could be, and the second after I finish, it's gone back to flaccid incredibly quickly.
5. I don't look like I work out at all because I am so oily and bloated and watery. I can barely see my abs unless I flex them hard, and I can't see the veins in them at all.



You will need to spend a lot of time going through the range of low and high e2 symptoms on your own personal journey over a long period of time to be able to understand what your own unique signals are. I'm still learning mine and I've been doing this for over 8 years now.
 
Here are my low e2 and high e2 symptoms. I pay very close attention to how I feel and very closely monitor my mental health, so I feel pretty confident with the explanations below. Also, historically I have tried countless times to dose an AI based on a predicted schedule of when I "should" need it, and I almost always ended up in low e2 territory. You will see that a lot of advise from people says to "monitor how you feel and when you know your e2 is high, you take an AI". I find that advice to be the most appropriate for me. I don't have endless money and time and schedule flexibility to just keep going to get an ultra-sensitive e2 test every 2 weeks.

Slightly/moderately low E2 symptoms:

1. I get more laser focused at work and I am able to concentrate on discrete tasks better. I don't laugh as often and jokes are more difficult to find funny. I am more serious and people are likely to ask me why I look so serious or angry. I can sustain my concentration better.
2. I wake up with more frequent and stiffer morning erections. In the past I have chased this as a metric, but I have learned this is not super valuable information to me as far as how well my actual sexual performance will go.
3. My elbows and knees may start to have some stiffness and I'll definitely be more aware of my joints during a workout
4. Thoughts will start to enter my mind that don't usually, and they are usually trending negative. Whatever problem is going on with me (particular if I'm in a relationship), my mind will find a reason to focus on that and see the bad outcomes or feel anger and resentment towards it.
5. I'll drop a lot of water and find myself peeing a lot more frequently. Visually I'll look dramatically better than I did a few days ago, because I'm suddenly very dry. I see veins on my abs more prominently. I look at myself and think "see why can't I look like this all the time? this is the way I'm supposed to look."
6. My appetite tends to go down
7. My workout endurance goes down and I find that I'm not as strong on max effort sets
8. I don't sleep as long
9. I'll have more acne that appears in the usual cystic acne spots (around my neck/shoulders/back/hips/chest)

Very/extremely low E2 symptoms:

1. Don't ever get to this point. If you experience the slightly/moderately low E2 symptoms, and you take more aromatase inhibitor before those symptoms have reversed course, you are going to regret it.
2. My mental health is the worst it's ever been. I hate everyone, even the love of my life. I can't stop the stream of unending bad outcomes and terrible bitterness or anger and resentment that has appeared out of nowhere about literally everything that bothers me.
3. I can't stay awake at all, but not because I'm lethargic (like a high e2 symptoms); rather, I can't stay awake because I feel physically exhausted by simply keeping my eyes open. Like I've run a marathon on 3 hours of sleep and 10 cups of coffee and no food. When I take anything with a stimulant, it doesn't work. At all.
4. My dick doesn't work entirely. Unlike the high e2 symptom where it becomes less hard during sex but generally still works, this is something else entirely. I've literally had a woman who I found very attractive give me oral for 15 minutes and my dick stayed small and flaccid. And I was filled with all sorts of unhealthy emotions when that happened because as you can imagine, I wanted it to work, but didn't understand why.
5. Furthermore, if you are extremely low E2, even taking Cialis or Viagra won't do anything. You need some estrogen for your dick to function, and if it's crushed, no amount of PDE-5 inhibitor will save you. Learned that one the hard way too.
6. You have almost no workout endurance at all. We're talking like, one hard set and you're done. You won't even want to train.
7. You will be peeing constantly and each time you feel like you have to piss, barely any liquid will come out.
8. Joints that you forget you have will start to hurt and pop, including your toes, the heels of your foot, and your hips and sacroiliac area. You will be very aware of your spine during all lifts and you may have generalized low back pain from simply sitting down.
9. I'll look in the mirror and look very small, and generally be disgusted with how I look, even though I am the driest I have ever looked. I will not be happy in any way/shape/form with anything regarding my appearance.
10. I'll have no new acne that appears

---

Slightly/moderately high E2 symptoms:

1. I'll start getting more acne in the usual spots, but it's usually not cystic.
2. My face will look slightly more oily
3. My body will appear like I gained more bodyfat rather suddenly, and my stomach will appear like I'm bloated for a very long time after I've eaten anything. Even when I wake up in the morning, I'm very aware of how fat my face and neck look, and it makes me question whether or not I'm truly eating like garbage.
4. I generally feel mentally pretty good. I don't really focus hard at work, but I tend to enjoy my life outside of work a lot more. I enjoy playing with pets more, and I am much more forgiving when shit goes wrong or things happen unexpectedly. I am more calm and more patient.
5. I'm feeling pretty lethargic and feel like I could have slept about 4 more hours after I got enough sleep. Coffee still works, but I need more of it than usual.
6. My dick still works, and during sex, it feels great, but I tend to finish faster than usual.
7. Really, overall, the main tells that I am at this point and I don't want to increase it further are the water retention and lethargic symptoms I describe in #3 and #5. Once these bother me enough, I'll take the smallest dose of AI I have and wait.

Very/extremely high E2 symptoms:

Everything described in the slightly/moderately list of symptoms, PLUS the following:

1. I have a high likelihood of crying during a sad movie, or when I think about my parents, or contemplate being alone. I feel like crying is a possibility during most things, and can't understand why I can't keep it together.
2. I have a very high likelihood of being triggered in my relationship by what my partner does, which will lead to feelings of jealously, irrational anger, rumination, and projecting things that my partner is thinking, when she isn't.
3. I don't feel like I have any self-confidence, and feel very needy and clingy with my partner, in a negative way. For example, during this time, the thought of my partner going off to hang out with her friends alone terrifies me. I get a range of thoughts such as "does she hate me? is she going to cheat on me? why do I always put her needs before mine when she doesn't do the same for me? why doesn't she love me the way i love her?"
4. My dick will still work, but unlike the low e2 symptoms, I don't have any sexual desire. It's sort of the inverse of the low e2 dick problem. In the low e2 scenario, I have a ton of mental desire for sex, but my dick WILL NOT move. In the high e2 scenario, I have very little if any sexual desire, but my dick could become hard if it was mechanically stimulated and/or I took Cialis and got oral. It just wouldn't be as hard as it could be, and the second after I finish, it's gone back to flaccid incredibly quickly.
5. I don't look like I work out at all because I am so oily and bloated and watery. I can barely see my abs unless I flex them hard, and I can't see the veins in them at all.



You will need to spend a lot of time going through the range of low and high e2 symptoms on your own personal journey over a long period of time to be able to understand what your own unique signals are. I'm still learning mine and I've been doing this for over 8 years now.
you notice that water retention is just as high wit crashed e? your body can’t absorb carbs wit h crashed e so it makes you watery an face look fatter
es so confusing cause both high and low symptoms are die same
 
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you notice that water retention is just as high wit crashed e? your body can’t absorb carbs wit h crashed e so it makes you watery an face look fatter
es so confusing cause both high and low symptoms are die same
agreed. in fact im experiencing a little of that right now as I write this. I took a small dose of anastrozole two days ago (which should last me a good 5-7 days before a redose) and ive noticed the watery look.

The thing that helps me stay grounded is the fact that I keep track of when I take AI and hormones on a calendar, and know by now how long a given dose of an AI lasts at a given testosterone dose. Since im currently in the process of lowering my weekly dose, my AI is likely getting stronger and Im dipping slightly more into low symptoms.
 

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