I'm curious....is this why you always feel fatigued?
Have you had it tested? The body converts more t4 to rt3 when you are sick, like the flu, to slow metabolism down to force rest and recovery.
I would assume things like an over active thyroid could also induce high rt3. If the body were under metabolic stress, it should reduce tsh to produce less t4, not continue to pump out t4 and convert to rt3.
There's a theory that rt3 can occupy t3 receptors, rendering t3 ineffective and giving hypothyroidism side effects but last I knew it was not proven, only theory. So, rt3 potentially has no side effects.
I've put many hours into thyroid research but it's been a few years, my memory is getting rusty.
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I've had high reverse T3 (with elevated prolactin and TSH) because I am hypothyroid and being treated with T4 which my body was not converting to t3 efficiently. I think most people would not have that issue, so please don't take my case as general advice.
A switch to Armour thyroid solved all the issues. It is hard finding doctors in the US that Rx armour. Armour is made from pig thyroid and contains all the different thyroid isomers (probably the wrong term), so if your body does not convert well it is not an issue.
This isn't really an accepted theory, non the less has some logic to it...**broken link removed**
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Symptoms if you did please? And how did you treat it?
thanks
Have you had it tested? The body converts more t4 to rt3 when you are sick, like the flu, to slow metabolism down to force rest and recovery.
I would assume things like an over active thyroid could also induce high rt3. If the body were under metabolic stress, it should reduce tsh to produce less t4, not continue to pump out t4 and convert to rt3.
There's a theory that rt3 can occupy t3 receptors, rendering t3 ineffective and giving hypothyroidism side effects but last I knew it was not proven, only theory. So, rt3 potentially has no side effects.
I've put many hours into thyroid research but it's been a few years, my memory is getting rusty.
Sent from my SM-G965U using Tapatalk
Carb up.
Eat more carbs, less protein.
Sometime you gotta take a break from protein.
Thyroid need carbs to function.
Make a High carb day where you only eat carbs during the whole day.
Were your numbers similar before you started taking T4/armour thyroid? My T4 is already on the high side so I might only need T3.
And what is your dose of Armour Thyroid?
Reverse T3 is inert and does not "block the receptors" as is commonly touted on the internet. There's not a lot of information in the literature about it, but it's a rate limiting step to control T4 to T3 conversion via the Deiodinase 3 enzyme. (D2 converts T4 to T3/ D3 converts T4 to RT3). Elevated Reverse T3 is more a sign and symptom, not a cause, of disease. Reverse T3 can be elevated after injury/surgery, starvation/dieting, and autoimmune disease/states of chronic inflammation.
The other common wisdom that is false is that T4 as an inert/inactive hormone. It actually has it's own effects independent of it's conversion to T3 and some tissues are better at converting their own T3 rather than using it from the serum pool. Higher Free T4 levels have been linked to well-being. https://academic.oup.com/jcem/article/91/9/3389/2656451
Fun fact: HGH increases the conversion of T4 to T3. In hypothyroid subjects taking 100-200 mcg of T4, their Free T4 was top of the range and Free T3 at the bottom. The HGH brought Free T4 down to mid range and Free T3 to the very top. ( Free T4 from around 1.8 to 1.4 ng/dLand Free T3 from around 2 to 4 pg/mL )
https://www.ncbi.nlm.nih.gov/pubmed/7828350
Exactly, there is a lot of data showing that high carbs upregulate conversion of T4 to T3 and low carb diets to the opposite.
High carb diets in some ways simulate caloric surplus even in a deficit, by upregulating leptin/T3/Etc.
I had low t4, low normal t3 and high TSH before any treatment. Had similar numbers before any PED use
Treatment with t4 only increased t4 and did not do much to help TSH or t3 levels. This was over 2 years of gradually increasing T4 with regular BW. I took GH for part of the time and it did not really help the conversion much.
Armour I started at 60mg, an currently at 120mg with normal bloods. The armour dosing conversions can be confusing... It is not in MCG, but is sometimes listed in "grains." Or just the MG like mine.
NH, I can’t believe you are still having this problem. This has to be unbearable. I sure hope you find of something soon.
I'm not sure if this is the same thing, but I recently was diagnosed with Grave's disease. Basically, it's a hyperactive thyroid. I had absolutely NO energy or strength, my cardio was non existent, sweating all the time in air conditioned rooms, I lost 20-25lbs in roughly 4-6 weeks, my memory was off, and my heart was beating like crazy. I thought I had cancer! I went to my primary and he admitted me to the hospital for a few days. They ran x-rays, MRI's, etc... and that's what they found. I'm om methimazole and propanolol and am doing much better.Symptoms if you did please? And how did you treat it?
thanks
16 months now. It's horrible. Lyme disease is still possible since I tested for several of the bands in my western blot test. But I have NO aches and pains like Lyme people usually have. I just don't get it.