I have only run Nolvadex because of all the moodiness I've heard Clomid can cause. I guess until I try the Clomid I'll never know if it will make me mr emotional. As for now the simple 3 weeks of Nolvadex works best.
You are best off stacking Nolv with Clomid... the nolv to block freeflowing estrogen absorption and the clomid to increase estrogen and testosterone production. Nolv blocks estrogen produced by the clomid, the clomid stimulates test production to compensate for the estrogen. If you were just to use one I would recommend Nolv over clomid, numerous test prove it far more effective.