There have literally been dozens of studies in the past few years showing the positive benefits of using Melatonin at various doses, and for various health benefits, especially for females. I was going to start a thread here on it, but figured it wasn't hardcore enough, lol. It's one of the few supplements that even Lyle McDonald has posted positively on over the last few years (not saying he promotes it either). Melatonin is very promising, but the dosing seems to be in question on what is ideal, and for what purpose. Also, like mentioned, higher doses show promise, but that doesn't mean much if the next day it makes the user feel tired and sleepy. I'd say experiment and use what dose works best for you.