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PCT, long read but is it better than the regular suggested?

Taeian

Banned
Joined
Feb 26, 2008
Messages
58
Ok so I writen this up after finding alot of studies from doctors etc suggestiong about clomid can be seen with results up to 4 months. But I am hoping some advanced people can help provide me with some proof or etc explaing why 4 weeks is enough for pct since almost EVERYone suggest 4 weeks of nolva. Can you keep recovering with novla for 4 weeks forever even as we get older? and have serveral cycles under our belts? cause I know my last cycle its taking me along time to recover still with 5 weeks of nolva. so here goes long read but what I have put together and i will be running myself.

The standard PCT everyone mainly suggest in all articles is a 4 week cycle of nolvadex therapy of 40/40/20/20 4 weeks long. Sometimes we see a PCT of 5 weeks long mixed with clomid. Sometimes kick starting the clomid at 300mg first day and rest 150/100/50. I have stumble across a few research studys and a few doctor test on clomid and nolvadex in men with low testosterone levels, Now these men could have ran cycles and some could just have naturally low testosterone levels, but the fact is they all have low levels much like we all do after a cycle.

The importance of having healthy normal or high levels of testosterone as many of us know is very important. Weather its to have a healthy libidio or feel healthy as a man, a big role of pct is keeping our muscle gains. So many young guys claim they are fine after 4 weeks pct just because they have erections like normal. But not alot know it only takes 200ng testosterone in a male to have erections. The normal range of testosterone for heathly men is around 200ng-1000ng depending on the doctor. The younger you are the higher testosterone you should have and as we age most of you know our levels decline and we end up in the low range.

It seems to many people don't get bloodwork done these days they just say they recovered fine after a cycle because they started sustaining erections again fully. Yet as I have pointed out above it only takes 200ng testosterone to attain one. And if we are only getting around that range that is going to be very bad for keeping muscle gains. Alot of the younger guys seem to claim they recover fine after a cycle with little to no pct. Yet alot of the older guys hittng 30+ seem to take months to recover and alot are going on HRT everywhere you look. Is this possibility because of the such short pct we have been running in our younger years? Sure after a cycle or 2 you will recover fine the body does. But when we start reaching 5 or 7 cycles of 10-16 weeks does that not take quite a toll on the body with such short pct, even more so with age!

Here is a study to read of men of all age's from 18-59 along with 40-70. I will point out some of the main facts in this writing.
General patient population
In the Center for Sexual Function, 990 men who presented with sexual dysfunction during a 2-y period were evaluated with retrospective chart review. The clinical characteristics and medical risk factors of the population were previously reported.25 All men had testosterone and luteinizing hormone levels monitored, and 58 men (5.8%) had hypergonadotropic hypogonadism (primary gonadal failure), while 302 men (30.5%) had hypogonadotropic hypogonadism (ie, low testosterone and inappropriately low or normal luteinizing hormone levels). Of these 302 men, 272 (90.7%) had ED as part of their presenting complaint, defined as the inability to achieve or maintain an erection long enough to complete sexual intercourse satisfactorily in more than 50% of attempts.
"Treatment with clomiphene citrate
Of the 272 men with hypogonadotropic hypogonadism and ED, 228 (83.8%) completed a 4-month course of clomiphene citrate, 50 mg orally on Monday, Wednesday, and Friday. Most of these men were married in a stable heterosexual relationship; the single men were in a steady relationship for at least 6 months. A home log was kept in which the couple recorded the number of sexual attempts and successes at intercourse. A successful response was defined as the ability to complete intercourse in more than 75% of attempts; a partial response was defined as successful intercourse in from 50 to 75% of attempts. The men who failed did not notice any change in their sexual activity. No men reported side effects caused by clomiphene citrate."
"Hormone testing
Of the 228 men who began taking clomiphene, 173 (75.9%) men completed the 4-month course of treatment and had similar blood tests performed in the same laboratory, the Central Laboratory of Lahey Clinic. This population was the basis of the present study. Serum luteinizing hormone and free testosterone levels were drawn between 08:00 and 12:00. Of these 173 men with low baseline testosterone levels, 116 (or 67.1%) had two or more low pretreatment testosterone levels measured 1–3 months apart, which ruled out the possibility of random fluctuations or laboratory error."
"Univariate analyses
The mean age of the 173 men was 54.3 y. A total of 84 men (48.6%) were under age 55 y (mean, 45.2 y), and 89 men (51.4%) were 56 y or older (mean, 62.1 y).
Figure 1 shows the response rate of the group as a whole. In all, 67 men (38.7%) had a positive response with a regular intercourse completion rate (>75%), 63 men (36.4%) had a partial response with an intercourse completion rate of 50–75%, and 43 men (24.8%) reported no change. Therefore, 75.1% noticed improvement in ED, with 38.7% returning to normal sexual function."
"Figure 2 and Figure 3 show that despite a disparity in clinical response, clomiphene stimulation significantly raised the blood levels of both luteinizing hormone and free testosterone in all groups. The serum luteinizing hormone level rose in the responders from 3.3 to 7.7 IU/l (P<0.001), from 4.2 to 7.7 IU/l (P<0.001 in the partial responders), and from 4.4 to 8.5 IU/l (P<0.001) in the nonresponders. The serum-free testosterone levels rose from 9.3 to 21.2 pg/ml in the responders, from 9.2 to 18.0 pg/ml in the partial responders, and from 9.8 to 17.6 pg/ml in the nonresponders (all significant where P<0.001)."
"Our data showed that clomiphene citrate can successfully stimulate the hypothalamus to cause increased testicular testosterone production. Stimulation with 50 mg of oral clomiphene three times weekly may be diagnostic as well as therapeutic. If the patient does not respond with at least a 75% increase in testosterone and a 100% increase in luteinizing hormone, further evaluation of the hypothalamic–pituitary area is warranted."
"Clomiphene stimulation did not elevate the testosterone level out of the normal range, but it remained in the middle of the normal range. Stimulation for 4 months produced levels similar to those in our previous study when the levels were measured after 2 months."
http://www.nature.com/ijir/journal/v15/n3/full/3900981a.html

This study makes me think that a PCT of nolvadex and clomid as doctors suggested would be best run at a protocol of 50mg clomid every other day and 20mg nolvadex everyday for a period of 2 months minium and best results around the 4th to 6 month line. As the studys indicate that results are still happening into the 4th month of clomd therapy.
Alot of steroid users like to think that nolvadex and clomid have really harsh side effects, while some of that is true from what I have found most side effects occur in 1 percent of users.
 
Clomid
"Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

breast discomfort
depression
dizziness or lightheadedness
headache
heavy menstrual periods or bleeding between periods
hot flashes
nausea or vomiting (not severe or continuing)
nervousness
restlessness
tiredness
trouble sleeping
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention."
**broken link removed**
Nolvadex
At a median follow-up of 33 months, the combination of anastrozole and NOLVADEX did not demonstrate any efficacy benefit when compared to NOLVADEX therapy given alone in all patients as well as in the hormone receptor positive subpopulation. This treatment arm was discontinued from the trial. The median duration of adjuvant treatment for safety evaluation was 59.8 months and 59.6 months for patients receiving anastrozole 1 mg and NOLVADEX 20 mg, respectively.

http://www.rxlist.com/cgi/generic/tamox_ad.htm
Alot of users seem to shy away from using PCT serms for so long cause of the side effects yet women with breast cancer use it for up to 59 months! Yet if so many are afraid of serms why do we run them at 300mg and 150 for clomid and nolvadex at 40mg? Why not stick with what the doctors suggest at much lower dosages and run for a longer period of time. And we all know doctors don't just hand out drugs they always shy away from it and only give you enough of the drug till the problem stops.
On another note of nolvadex if anything it should possibly be ran through out cycle if you have a history or family history of heart problems and or strokes.
Nolvadex:

"This suggests that tamoxifen reduced the buildup of cholesterol (plaque) and reduced the arteries? rigidity, both risk factors for heart attacks. In fact, the arteries of those who took tamoxifen resembled those of a younger person with no coronary artery disease The men taking tamoxifen also showed lower levels of cholesterol, triglycerides (a type of fat in the blood), lipoprotein(a) (a special fat-protein combination), and fibrinogen (a blood-clotting substance) ?all additional risk factors for heart disease."
"These tamoxifen benefits went beyond those seen in the men who took only the cholesterol-lowering drug. Take-home message: While this study was very preliminary and small, the results suggest that tamoxifen?and perhaps other drugs within the same family?may help reduce the risk of heart disease. Tamoxifen belongs to a class of drugs known as SERMs, selective estrogen receptor modulators, which mimic the actions of estrogen in some tissues of the body."
**broken link removed**
Conclusion
With all the benefits these serms have it seems there is no reason to not run them the period which doctors suggest. Even more so with studys proving side effects are in the 1 percent range. With so many users running AAS cycles of up to 20 weeks any the average user anywhere from 12-16 weeks and of course the users that do not come off. Would it not be in there best interest to run PCT the same length of cycle if not longer like the doctors suggested 4-6 months? Remeber our HPTA system goes into hibernation when on cycle cause all the rush of hormones were injecting or orally ingesting is telling our brains to stop producing anymore hormones as there is enough in the body. So with our bodys HPTA axis in hibernation for up to 20 weeks at a time are we really going to just bounce back in a couple weeks? Sure the young users do in a matter of abit, atleast there libido. But it seems these young users in a few years and a few cycles are going to be like the rest of the older steroid users. They are going to take months to recover even after there 4 week pct is over.
I am thinking after reading these studies myself we can help further prevent having such hard recoverys and actaully help keep our levels for years to come at a very heathly level. As the studies states most men in the clomid therapy got levels that of men 20 years young. Yet you see alot of steroid users running 4 week pct by the time they hit there 30s there natural testosterone production just keeps getting lower and lower after each cycle and eventually like most end up on HRT for life. Can these longer PCT protocols prevent this? And keep us off HRT when we get a little older?
From the time I've been collecting knowledge of AAS and related topics such as PCT, I have always seen the standard 4 weeks told to any user, and once in awhile see someone suggest 5 or 6 weeks but that is it. But I don't think thats enough from what I have seen, maybe someone else can enlighten me and show me some proof to that 4 weeks can fully recover a steroid user that has a few or several cycles under his belt, such as bloodwork or studies.
 

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