Toremifene, Clomiphene, and IGF

[sakguy]

I know that Tamoxifene has been shown to decrease IGF-1, but how about Toremifene or Clomiphene. Do these have an affect on IGF-1, or if so, is their impact as harsh on IGF-1 levels as Tamoxifene.

 

[sakguy]

bump, nobody?

 

[Conciliator]

I'd expect both of them to lower IGF-I, though I'm not aware of any research on them. Most anti-estrogens, including arimidex and letrozole, have been shown to lower IGF-I levels.

If you're interested, DatBTrue has said "it would seem that male bodybuilders who use low dose Tamox in a PCT need not be concerned about inhibition [of IGF-1 production]." The endocrinologist Swale then stated "I wish this simple point would spread across the Boards to dispel this widely accepted nonsense."

Personally, I wouldn't be worrying about IGF-I and the use of an anti-estrogen. If you need an anti-estrogen, then you need one. Just use it.

 

[K-fed]

Clomid is not as hard on IGF-1 levels as Nolva. I like to let my estrogen levels run high for the first two weeks of my cycles before I add in my AI's and so I use an estrogen antagonist to keep gyno and other sides in check during this time. Only problem is Clomid just doesn't seem to do the job for me as I'm VERY estrogen/gyno prone and therefore I use Nolva since its the stronger of them. I wanted to try and keep my IGF levels running high but like the above gentleman stated.... When you need one you need one. Just take it. I wouldn't think it could make that much of a difference.

 

[Conciliator]

Clomid is not as hard on IGF-1 levels as Nolva.

Do you have a reference for that? If so, I'd be interested to see it.