im not doing ED but went to twice a week from once a week, I felt fine at once a week but thought I would try to optimize, 150mg once a week had a trough of 650, went to 80mg twice a week and tt trough was 1215, so started cutting dose, I really think I will try back to once a week, I talked to a couple of guys on another board and they went back to once a week and their hematocrit dropped by 2 points, but im getting surgery in about a week so that shit will have to wait, once I do it I will report results here but it will be awhile.