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Aromatase Inhibitors vs Estrogen Blocker

xcelbeyond

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Interesting Post from AE by tanksalot

These 4 compounds can be put into 2 distinct groups; aromatase inhibitors and estrogen blockers.

Aromatase inhibitors prevent the aromatisation of testosterone to estrogen, thus lowering circulating level of estrgoen in the body. Arimidex and femera fall into this category. It is thought that femera is stronger than arimidex and thus greater supression of estrogen can occur.

Estrogen blockers prevent estrogen from acting on the recpetor sites in certain tissues (i.e mammary) but DOES NOT lower circulating estrogen levels. So if clomid/nolvadex is stopped abruptly whilst estrogen levels are still high you will experience estrogenic effects.

Usually arimidex/femera is used post cycle in conjunction with clomid/nolvadex to keep estrogen levels low. There is at least one good reason for this. When natural levels of hormones rise estrogen rises more rapidly than testosterone thus presenting the user with problems, even the use on an anti-e is sometimes not sufficient to blunt these effects, so an aromatase inhibitor is the better choice.

From your next cycle an anti aromatase is not strictly needed for the duration as there will be no aromatisation from the AAS you mention. If one can be afforded however it would be good to add because it appears to limit fat build up (especially when combined with tren). So if you are strapped for cash you could just use the aromatase inhibitor post cycle with the usual clomid therapy.

xcel
 
Yup I use both anti aromatase and estro blocker together, on AND off cycle. Clomid and arimidex.
 
MikS

What is your protocol for this? Dosages and lengths, etc.
 
Does anyone know what classification exemestane is in??

xcel
 
I'm pretty sure it would be considered an aromatase inhibitor. It is calle a "suicidal" one because it completely destroys the aromatase enzyme, while I think arimidex and femara only occupy the aromatase enzyme
 

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