if i dose an amount of exogenous insulin to match a certain carb intake why does that promote more anabolism than my body's natural response to the same amount of carbs? Wouldn't the insulin amounts be farely similar, given that neither scenario makes me hypoglycemic? Just curious abt the physiology at play.
And let's remove a scenario like GH use where the exo slin overcomes some insulin resistance from the GH
I've been asking this question myself for years. I've read almost everything I could find on the topic and experimented with different forms of insulin quite a bit a couple years ago. I've never experienced any dramatic changes like the ones you get from AAS, but I have to say I was the biggest I've ever been during that time. I mainly used short and intermediate acting insulin like Humalog and Humulin-R the way Mike Arnold recommended around the workout. I also tried Lantus a couple of times but no matter what kind of insulin I took, I went hypo so many times even with doses less than 5 iu's. I did make sure I had AT LEAST 20g of carbs per 1 unit of insulin and I did time it correctly and monitored my BG levels. I even went hypo once from 15 ius of Lantus, which everyone would consider impossible. Going as high as 100 iu's of Lantus and more like Mike recommends seemed like suicide to me.
When my insulin sensitivity is obviously so good, I just don't know if a couple iu's more are doing much and are worth the effort.
I have to say I never pushed the calories during that time. I was mostly in an isocaloric state. I had around 250g of carbs around the workout split into a pre-workout meal, intra workout shake and post-workout meal but the rest of the day, I kept my carbs and calories pretty low. As far as I can remember I took about 10-15 ius of Humulin-R, that was the most I could handle without going hypo.
Maybe I would have had better results when I pushed the carbs higher.
My new theory to your question is, a supraphysiologic amount of insulin through the administration of exogenous insulin may allow your muscles to temporarely store more glycogen than they could with an amount your body produces endogenously. But this requires you to consume MORE carbohydrates than you'd do in an isocaloric state. I just don't know much of a difference it makes when AAS and GH are already used as they increase muscle glycogen synthesis to a large degree by themselves as well.
There may also be some additional benefits with the activation of IGF-1 receptors and IGF-1 production in the liver but when I'm going to use it again, I make sure to push the carbs higher than I used to