In the short term no, in the long term yes. The acute effects of taking a DHT derivative, or anything else, for a little while can be very different from the chronic effects of long-term use or abuse. And of course the dose makes the poison, as with any drug, taking small or reasonable doses can be very different than shotgunning huge amounts for a long time.
Like most things, the best answer is "well, it depends..."
Personally, I have found that taking reasonable doses (no more than 50mg Proviron per day, or an equivalent amount of Masteron per week) only helps things in that regard. YMMV.