For my summer cut I want to throw in 20mcg of Clen for fasted cardio in the morning.
However I'll also add in 3IU of growth which really jacks my heart rate up. Without nebivolol my resting heart rate will be 90+. I remember sitting in the sauna and my watch was giving me warning my HR is going to high while I'm not active. 2.5MG nebivolol takes care of that problem.
However logically it just seem like a beta blocker may cancel out many of clens benefits.
But the upon further reading Clenbuterol primarily acts as a selective beta-2 adrenergic receptor agonist. This means it stimulates the beta-2 receptors found in various tissues, including the bronchial tubes, skeletal muscle, and adipose (fat) tissue.
While Nebivolol Nebivolol selectively blocks beta-1 adrenergic receptors in the heart. These receptors are part of the sympathetic nervous system and are usually stimulated by the neurotransmitter norepinephrine. By blocking these receptors, nebivolol reduces the effects of norepinephrine on the heart. This results in a decrease in heart rate and the force of heart contractions, which leads to a reduction in blood pressure.
So since they hit saperate receptors it would be ok to run them together? I'd appreciate some insight on those that know the pharmacokinetics of these two compounds. Thank you.
However I'll also add in 3IU of growth which really jacks my heart rate up. Without nebivolol my resting heart rate will be 90+. I remember sitting in the sauna and my watch was giving me warning my HR is going to high while I'm not active. 2.5MG nebivolol takes care of that problem.
However logically it just seem like a beta blocker may cancel out many of clens benefits.
But the upon further reading Clenbuterol primarily acts as a selective beta-2 adrenergic receptor agonist. This means it stimulates the beta-2 receptors found in various tissues, including the bronchial tubes, skeletal muscle, and adipose (fat) tissue.
While Nebivolol Nebivolol selectively blocks beta-1 adrenergic receptors in the heart. These receptors are part of the sympathetic nervous system and are usually stimulated by the neurotransmitter norepinephrine. By blocking these receptors, nebivolol reduces the effects of norepinephrine on the heart. This results in a decrease in heart rate and the force of heart contractions, which leads to a reduction in blood pressure.
So since they hit saperate receptors it would be ok to run them together? I'd appreciate some insight on those that know the pharmacokinetics of these two compounds. Thank you.