Certain bacteria seem to promote favorable antibody ratios. Increasing IgA levels, decreasing IgE levels. Shifting the immune system to reduce allergic response while promoting strong pathogen response.
L. Paracasei, L. Reuteri, L. Gasseri and many others have been shown to have beneficial immune properties. The problem is many supplement companies do not list the SPECIFIC strain used and in studies only particular strains are effective.
So it isn't as simple as taking any L. Gasseri supplement. Is it the
KS-13 strain that was used in studies? Do other strains also retain the same biological effect, probably not.
https://www.ncbi.nlm.nih.gov/pubmed/16054520
https://www.ncbi.nlm.nih.gov/pubmed/25909149
http://www.ergo-log.com/lactobacillusreuteri.html
Curcumin and Resveratrol for example can
lower immunity towards pathogens.
Resveratrol and curcumin suppress immune response through CD28/CTLA-4 and CD80 co-stimulatory pathway
Sharma S, Clin Exp Immunol. 2007 Jan;147(1):155-63
Resveratrol Stimulates Cortisol Biosynthesis by Activating SIRT-Dependent Deacetylation of P450scc
"The most striking findings were that both resveratrol and curcumin suppressed the activity of T and B cells and macrophages, as evidenced by significant inhibition in proliferation, antibody production and lymphokine secretion. Interestingly, curcumin imparted immunosuppression by mainly down-regulating the expression of CD28 and CD80 and up-regulating CTLA-4. Resveratrol also functioned by decreasing the expression of CD28 and CD80, as well as by augmenting the production of interleukin (IL)-10."
Resveratrol Stimulates Cortisol Biosynthesis by Activating SIRT-Dependent Deacetylation of P450scc
Donghui Li, Endocrinology July 1, 2012 vol. 153 no. 7 3258-3268
Resveratrol and curcumin suppress immune response through CD28/CTLA-4 and CD80 co-stimulatory pathway. - PubMed - NCBI
"By modulating cortisol production, resveratrol may act to modulate glucocorticoid-dependent physiological processes. Of note,
resveratrol has been found to act as an immunosuppressant."
Both resveratrol and curcumin suppress:
-the proliferation of T cells and secretion of IFN-γ and IL-4;
-the proliferation of B cells and production of IgG1 and IgG2a isotypes;
- proinflammatory cytokines (IL-1, IL-6, TNF-α) but enhances the levels of anti-inflammatory cytokine IL-10;
-both resveratrol and curcumin down-regulates the expression of CD80 and CD28;
-curcumin but not resveratrol up-regulates the expression of CTLA-4; and
-both curcumin and resveratrol fail to modulate CD4+ CD25+ regulatory T cells and expression of CD40.
Glutathione has fantastic immune properties. Quercetin that actually absorbs such as the
Iso form.
Liquid olive leaf extract in a recent studied had much higher absorption than taking an olive leaf pill. The plasma concentration was significant.
Results from taking liquid olive leaf vs regular pills:
https://www.ncbi.nlm.nih.gov/pubmed/23766098
Zinc
Acetate in particular has some interesting science behind it. How it increases interferon levels, how it can migrate up the sinuses even though you are using it as a lozenge. How it can block receptors that common cold viruses need.
One study that I THINK Ajinomoto conducted on NAC and Theanine found that in athletes, their immune function did not deteriorate like the placebo group. This is most likely because L-Theanine is used in the formation of interferon.
http://www.ergo-log.com/combination...-chance-catching-cold-by-seventy-percent.html
**broken link removed**
From
**broken link removed** :
"
A distinctive amino acid that is found in minute amounts in tea (Camellia sinensis), theanine exerts a significant effect on the immune system, by activating—in the event of bacterial infection—gammadelta T cells to a state of readiness.1 These cells, comprising a line of defense among total peripheral blood T cells, are mobilized (expanding by up to 50-fold) in response to bacteria, and theanine acts as the precursor to an antigen that primes gammadelta T cells in a manner that is like cocking a gun, pulling its trigger back.
This doesn’t directly result in firing, but it prepares the immune system to invoke gammadelta T killer activity against bacteria, while increasing the speed of action."
Ultimately the best practice I have found is using SinuOrega. It is a product that uses saline, oil of oregano, and some other essential oils that you spray in your sinuses. It clears out the sinuses and also has anti-microbial properties. If I feel exposed to some heavy sneezing or coughing, as soon as I get home I will use it. Same with the Zinc lozenges and this Yogi Throat Comfort tea that coats the throat itself.
Basically protecting my nose and throat really decreases the occurrence of colds. I wish our western society adopted the practices used in Japan where wearing masks when you are sick is not frowned upon but actually encouraged.
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seen it three times personally, two who were treated for cancer, the other one for hepatitis C... major aggressivness, loss of rationality, suicidal ideas, you name it... 
