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MK-0677

belixxx

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Registered
Joined
Jan 11, 2010
Messages
110
Some research on mk0677.

http://www.ncbi.nlm.nih.gov/entrez/q...t_uids=9467534

Summary of Study: Raises serum IGF-1/IGFBP-3, able to REVERSE diet induced nitrogen wasting (protein catabolism due to calorie restriction).
Done on healthy volunteers.



http://www.ncbi.nlm.nih.gov/entrez/q...t_uids=9349662

Summary of Study: Sleep patterns were less interrupted, REM and deep sleep was significantly increased. Done on healthy volunteers of age 18-30. Effect was seen much greater in elderly subjects.



http://www.ncbi.nlm.nih.gov/entrez/q...t_uids=8768828

Summary of Study: 7 day study on GH/IGF-1 effects after once daily administration. Showed similar GH release in all three concentrations (placebo/5mg/25mg) but dose dependant increases in serum IGF-1 in 5mg/25mg. Also showed an increase in GH pulses. Done on 9 healthy young males.



Design and biological activities of L-163,191 (MK-0677): a potent, orally active growth hormone secretagogue

This text shows the full chemical structure of MK0677 as well as how to synthesize it, available also in PDF. (It is referred to as L-163,191). Anybody wanna homebrew? :D Shows btw that oral availability is >60% and that it can form solution with water greater than 100mg/ml.



N-[1(R)-[(1,2-dihydro-1-methanesulfonylspiro[3H-indole-3,4'-piperidin]-1'-y l)carbonyl]-2-(phenylmethyloxy)ethyl]-2-amino-2-methylpropanamide methanesulfonate is MK-0677



http://patft.uspto.gov/netacgi/nph-P...y=PN/5773441

Patent information regarding ibutamoren mesylate.
 

juced_porkchop

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Jan 28, 2008
Messages
499
Thanks alot!

Just started this with my tren/test cycle (and cjc and igf1lr3 and igf1EC)
 

belixxx

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Registered
Joined
Jan 11, 2010
Messages
110
You're very welcome :)

Almost forgot about the compound... (Am on GW501516 currently)

Can you report anything? What dosage are you using? Is it from the board sponsor canadapeptides?
 

Canadapeptides

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Feb 8, 2012
Messages
59
I carry this until the 23rd when Health Canada deadline expires.

I sold a kidney to get this product. Not cheap, but kick ass mofo!

lol, you can't homebrew this unless you have a few semesters behind your belt silly goose! lmao jk jk jk

CP
 
Last edited:

belixxx

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Joined
Jan 11, 2010
Messages
110
Somebody in the know might translate the results of this last study to human, lol :)

What did it do, what didn't it do. What can we expect, etc.
 

Kronis.

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Registered
Joined
Dec 10, 2009
Messages
106
Somebody in the know might translate the results of this last study to human, lol :)

What did it do, what didn't it do. What can we expect, etc.
raised igf-1 levels by ~100ng/ml after 30 days at 25mg/day.
 

belixxx

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Registered
Joined
Jan 11, 2010
Messages
110
Could this be expressed in x many ius of gh/day usage, or cjc/ghrp usage or potential real world results usage to be more picturesque for the ones unfamiliar with the results of such IGF-1 level icreases?
 

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