I am actually entering into an extended "off" period. However, my past two blood work results showed elevated liver enzymes beyond the "normal" or "average" ranges. These were taken like 8 weeks post cycle and I have never actually had them done while "on". I am convinced that the eleveated AST, LST and CK are due primarily to muscle damage from training as these enzymes are present in other tissues and organs of the body and may leak from the muscle following intense weight training workouts. My GGT which is more liver specific was within the norm. So personally, I feel that the results gathered were overestimated in terms of liver damage or stress. Regardless, I am interested to see if the Synthergine has an impact on the outcome. In the past I have used loads of Milk Thistle, Sillymarin and Garlic in efforts to cleanse blood and liver but showed little if any benefit.