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ive been running Adex through my doctor at .25mg every day for 7 years now and have absolutely no issues with lab work every 6 months. Lipid profiles always perfect along with all the other tests we run. Estrogen always comes in around mid 30s. Low 30s is where doc wants it but mid-30s is acceptable. Anything over 40 or under 20 and you are worse off then with the adex. High or low estro leads to much more severe health problems long term in my opinion.
I'm surprised you're still in the mid 30s with 1.75mg per week. What's your Test dose?
According to this Dangers of Excess Estrogen in the Aging Male - page 1 | Life Extension you don't want your estradiol much over 30
You're lucky. But that's not a huge dose either. Arimidex and other AIs (letrozole, exemestane) are notoriously hard on cholesterol levels. They will drive good HDL very low in a majority of people if used heavily. Any AI is not great for lipid profile, but heavy use of AI will impact most people's blood work. It's best to use as little as absolutely necessary for HRT or cycling.
When I was using 2mg of adex per week my HDL went down to ~70 to 55 or so. Still good but a very noticeable drop. On 1mg of Adex though I went back up to mid 60s and my recent lipid profile was
Total Cholesterol: 182
HDL: 75
LDL: 98
Triglycerides: 31
So it's fantastic on 1mg adex per week
Having said that, I don't think one can conclude they aren't experiencing any side effects just because their lipid levels or even blood work on the whole is good. There are plenty of issues that can arise that will not show up on standard blood work (and I see too many people convinced they're completely fine just because they have normal standard lab values).