Adex already slightly lowers IGF levels, so adding IGF would be much more benefitial. Its not like its gonna be less effective. I don't buy into the whole lowering IGF levels on stuff like adex and nolva unless your taking a shitload of it. If you wanna play it safe, use aromasin instead. It raised IGF levels and is just as good of an anti-e as adex if not better. Expensive though. I know a research site that sells it fairly cheap though. PM me if you want it.