well, its not like there have been any studies done or anything..
but, i think its kind of inevitable. If you stay on TOO long, on TOO high of dosage, your body will forget how to produce insulin (youre now a diabetic).. Although, there isnt any real evidence.. this has never been actually PROVEN...and i know a few guys who, workout after workout, month after month, take 15 IUs.. I wouldnt recommend it.. 4 weeks on max. with at least 4 weeks off.