- Joined
- May 9, 2010
- Messages
- 356
Not sure about the high dimer theory.It's the opposite: GH promotes hyperglycemia (increased blood glucose), and so rhGH counters the rhI-induced hypoglycemia (decrease to blood glucose) when the two are used in combination ("slin+GH").
Fatigue/lethargy induced by rhGH is attributable to its impact on the adrenocortical system (promotion of the conversion of cortisol to inactive cortisone) acutely. The increase to serum IGF-I countervails somewhat the hyperglycemic effect, but it would be highly atypical in solo rhGH users to suffer from hypoglycemia/low blood sugar (quite opposite). Rather, the effect on cortisol is the issue. So-called "high dimer" values in particular rhGH preparations also seem anecdotally related to lethargy/fatigue.
Pharm gh (both genotropin and especially omnitrope) tend to make me unbelievably tired.
I have to cut my dose in half when using pharm grade or I'm completely useless.