My uncle had a pretty bad reaction to a statin when first prescribed. I was hesitant for a long time but I run pretty high rbc and hematocrit and there is a study with that combined with higher ldl/tris where statin made a massive difference in stroke risk (was going to be a long study but results were apparently overwhelming very quickly). Anyway I'd done just about all I could with diet/activity basics (made major progress but not all the way) and doctor got me over the hurdle. My ldl and tris are amazing now though I'm still working diet and other angles hard as I can. I take atorvastatin 10mg daily.