That depends - let me give you something to look for, from start to finish. At recon are you having trouble fighting off the bubbles when injecting the water? If not, that's the first sign of concern. Further, bubbles forming at this stage do minimal (if any) damage.
Next I'd try one or two good shakes -- that should produce at least a bubble or two. These bubbles should also remain for a very long time. The longer they last, the stronger the protien. FYI - this can hurt the GH, but not to the point it's useless. Hardly.
If nothing still, a vigorous shaking should produce something. It's at this point you can do some good damage to the GH. Still if nothing is produced, I'd be changing suppliers as you can do far better.