- Joined
- Apr 9, 2021
- Messages
- 1,723
I'll throw my opinion into the ring here.Thanks for all the comments, much appreciated! However I must admit that I don't agree with most of them
In the last 10 years, I've watched thousands of videos covering all aspects of bodybuilding. John Meadows, Scott Stevenson, Justin Harris, the Hypertrophy Coach, Greg Doucette, Chris Bumstead, the list goes on. Recently I've been watching Anabolic Bodybuilding by Big Dave a lot, great YouTube channel. I really eat and train in a very similar way to all these guys, and just as hard. I've trained at dozens of gyms in my life and was always in the group training the hardest and the smartest. I'm consistent, even when I go on Holidays first thing I do is finding a local gym to avoid skipping workouts. I take a week off training once or twice a year to let the joints and tendons recover, that's all. I never skip meals, always count macros.
I can't only complain either, I look now much better than before starting TRT and cycling. But it's like my body just doesn't want to grow past a certain point, maybe my natural myostatin levels are abnormally high. Whenever I start eating above maintenance, even on a quite heavy cycle, all these excess calories turn mostly into fat and not muscle. Even if the diet is super clean, basically chicken breast, white fish, lean beef, rice, vegetables and a little bit of fruit and nuts 7 times a day.
Take Ron Harris for example. Even though he tried, he never reached the size of a Pro, because he didn't have it in his genes. And he considers himself rather blessed genetically, on the "above average" side of the scale for sure when it comes to hypertrophy potential. I'm probably on the very bottom of this vast genetic scale, you blessed guys probably can't even imagine, some of you even want to send me to the beginners forum, that's mean to say the least haha
Well I was hoping that maybe it would turn out that I'm a hyper responder to HGH and that it would help me get to a lean 200lb, but it's most likely not the case...
GH response is determined by the increase to circulating IGF-I and is related primarily to polymorphism of the GHR gene (i.e., d3 homozygous confers great sensitivity, fl homozygous poor sensitivity) as well as factors like hepatic/liver health, body fat % (better to be leaner), etc. The GHR gene is rather separate from physiological determinants of androgen response (e.g., AR gene, where the length of CAG repeats determines sensitive to a great extent).
So yes, rhGH may yield significantly better results for you if you are, for example, d3 homozygous in the GHR gene and otherwise have great GH response.
Of course if you're a relative nonresponder to training stimuli due to other factors you may be out of luck for any dramatically improved training response.
Since most guys here are genetically endowed or blessed (it is ProM after all), you're not likely to find many that appreciate the wide divergence in the factors that influence muscle anabolism and body composition.