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Proteinuria facts

drgoodbody

FOUNDING Member
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Jun 5, 2002
Messages
790
Below are a couple of PM's that I think may help some of you who are concerned about protein in your urine.

---------- Phil's levels ----------
My creatinine levels were 1.9 and I am excreting 5300 mg protein in my urine over 24 hours.

---------- My reply ----------
Phil,

Those levels are both very, very high; the top end on normal creatinine is 1.4 mg/dL and for 24 hour protein excretion its 150 mg. It sounds like you have a bad case of Proteinuria and I would suggest you see a Nephrologist (kidney specialist) ASAP.

Proteinuria refers to the presence of protein in the urine. In healthy persons, the urine contains virtually no protein or only a trace amount of protein. Proteins in the urine are comprised of albumin and globulin from the plasma. Because albumin is filtered more easily than globulin, it is the predominant type of protein that may appear in the urine. The term albuminuria may be used interchangeably with proteinuria.

Detection of protein in the urine, combined with a microscopic exam of urinary sediment, provides the basis for the differential diagnosis of kidney disease. Normally, the glomeruli prevent passage of protein from the blood to the glomerular filtrate (the glomerulus being the filtering apparatus of the kidney). A small amount of filtered plasma proteins and proteins secreted by the nephrons can be found in normal urine; the normal range of protein excreted in a 24 hr. period is typically less than 150mg. Of this 150, 5-15 mg is albumin and the rest is composed of over thirty different types of renal proteins. Your doctor should probably have the excreted protein fractionated to determined what is causing the proteinuria. Excretion of mainly albumin may signify a glomerular lesion. Glomerular injury also causes increased permeability to plasma proteins, resulting in proteinuria. Generally though a persistent finding of proteinuria is the single most important indication of kidney disease.

Proteinuria is described based on the following scale:

Trace = less than 150 mg/24 hours (upper limit of normal)
1+ = 200 - 500 mg/24 hours
2+ = 500 - 1500 mg/24 hours
3+ = over 2500 mg/24 hours
4+ = over 3000 mg/24 hours

As you can see Phil, you are a 4+ on this scale - that concerns me greatly. Please go see someone.

DrG

P.S: Protein in the Urine is not normal. It is a symptom of something happening in your body. While the more concrete signs of kidney damage are the BUN (Blood Urea Nitrogen) and Creatine Serum Blood ratios along with the Creatine Clearance test, you still need to find out why protein is in the urine to begin with and hopefully stop more damage from occuring.
 
Now the BIG question

Is this the result from steroid use or high protein intake?

Or is it something that can occur in anyone and something "everyone," not just "users," or high protein intake should be cognisant of?

xcel
 
it can occur in anyone.. the condition has been around long before roids.. but, too high a protein content may exaserbate the condition in those prone to it...
 
LATS said:
it can occur in anyone.. the condition has been around long before roids.. but, too high a protein content may exaserbate the condition in those prone to it...

i tend to agree... now it concerns me about a lot of people having kidney problems.... seems like a lot of bodybuilders are starting to have problems.... but then maybe i am just more aware because it is my interest... at any rate i am super paranoid now.
 
Spoke to my physician a while back about this as I had a 24 clearance done. My levels were normal. I was told that the research is definitely there to support the theory that too much protein in unhealthy kidneys can accelerate kidney disease. However, the research is still out on too much protein causing kidney disease in healthy kidneys. I'm somewhat inclined to think any kidney disease in bb's that you see may come from micro vascular disease from not controlling their high bp. Just my 2 cents.
 
MINAMEEMANIMNM said:
http://www.nealhendrickson.com/mcdougall/030300purestrictprotein.htm
heres an article on to much protein and its tole on the kidneys

Thanks,

But this study did not take weight training men into consideration, only sedentary women, some of whom already had problems, as referenced by the only study this article sited.

1) Knight EL. The impact of protein intake on renal function decline in women with normal renal function or mild renal insufficiency. Ann Intern Med. 2003 Mar 18;138(6):460-7.


Weight training increases the need for protein because of the hormone release that it causes, and adding in AAS will increase that need even higher.
 
littlemack said:
I was told that the research is definitely there to support the theory that too much protein in unhealthy kidneys can accelerate kidney disease.
I actually read about a study which suggested that "high" protein could slow the progression of kidney disease. It was in an article by Layne Norton on bb.com
 
High Creatinine Levels in urine

Just returned from the kidney doctor after having slighly elevated creatinine level for several tests (1.7). Doctor told me that it maybe normal. The higher a person's lean body mass, the higher the creatinine level in the urine. He told me he had a firefighter that weighted 300lbs, all muscle and he had a 2.0 level that turned out to be normal for his lean body mass.

Protein in the urine is another issue, and will need to be investigated by a kidney specialist.

::tar-wars
 
Phil's quote

PHIL HERNON said:
IF I EVER START PISSING OUT PROTEIN WILL YOU PLEASE DRIVE ME TO A NEPHROLOGIST ASAP. OH ONE MORE THING, MAY I BORROW A KIDNEY?


Looks like it's time to go to the doc, eh?
 

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