Some info to focus us
As fathead pointed out, learning to manipulate your own insulin is very important. Do this before even thinking about insulin injections. I for instance do this when bulking by consuming a large liquid "meal" during my workouts (1700+ kcal - 150g protein) so I am hyperinsulinemic right after the workout.
(Dave, FYI: you have meant to say *hypo*glycemic above, I believe, not *hyper*glycemic.)
According to endocrinologists and other people w/ expertise (academic) in this area I have spoken with, insulin is considered to be the MOST anabolic hormone, even more so than testosterone. (Partly b/c it acts on so many tissues, but that's another story.)
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-The standard rule (for hum R) is 10g for carbohydrate for each IU injected, immediately post injection and again 2hr afterwards. If you for instance were to inject 8 IU (subq) that mean two 80g carb meals. BUT, carb entry will depend upon:
-Type of carb (GI)
-Timing of your last meal
-Protein and Fat in your meal.
-Water w/ the meal
-Gastric distention
-Etc.
If you ate 80g of carbs from fibrous veggies along with 4 chicken breasts (or 4 small steaks), I wouldn't be surprised if you went hypo.
Going hypo also depends upon insulin sensitivity, which is a funciton of:
-Timing of last meal (insulin's cellular effects last for hous after it has cleared the blood)
-Genetics
-Bodyfat levels
-Other beyond this scope
Insulin entry from the site can also vary accoring to vascularization, blood flow there and skin temp (will affect blood flow).
If you took in, say 20g of carbs / IU - shoot 8IU and take in 160g carbs at each of two meals, I can't imagine someone going hypo.
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As far as sides, Pancreatic (beta-cell) atrophy or apoptosis (cell death) is the one I'd be worried about. The fear is that the pancreas simply wouldn't function well b/c it is not used. This would be akin to testicular atrophy after gear use.
Another concern might be return of insulin sensitivity, but I don't imagine that would be a problem, either.
Take an example: someone takes 10IU @ 8 AM(postworkout a). Out of system at noon. Another 10IU at 6PM, out of system at 10PM. 2 -3 meals during the day where the pancreas will function "normally."
This person will have been on exogenous (injected) insulin for 8 hr, leaving 16 hr for pancreatic function to normalize. (It is more complicated than this, I realize, but I hope you see my point.)
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There are people all over the place who don't plan well, have ADD or suffer some kind of freak accident / mishap. Insulin CAN screw you up. So can gear. So can weight training. Most accidents occur in the home (in the kitchen I believe). You can pull a muscle wiping your ass... (OK, sorry
)
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I faintly recall hearing / reading of some reports of people like dave's buddy who were hospoitalize b/c of (or supposedly b/c of) insulin use (non-diabetics). Anyone have any links?...
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Just my $.02
-Randy