I don't see any mention of cross-linking in this product, which is important if it's to remain at the injection site. It's just called "Pure sterilized Hyaluronic Acid powder."
1. Tezel A, and Fredrickson GH. The science of hyaluronic acid dermal fillers. Journal of cosmetic and laser therapy: official publication of the European Society for Laser Dermatology 10: 35-42, 2008.
"Such a solution is known as free HA, uncrosslinked
HA, or non-modified HA. If this solution
was to be used as a dermal filler, the product would
be rapidly eliminated from the injection site (in less
than a week). This results from the very limited
residence time of uncrosslinked HA polymers in the
skin as the body quickly breaks down HA chains that
are not crosslinked into a gel (see below). Enzymes
such as hyaluronidase and free radicals that are
naturally present in the skin can quickly degrade
uncrosslinked HA polymers, cleaving off large
portions of the polymer chains at a time. As a result,
its half-life is 1–2 days in tissue, where it undergoes
aqueous dilution and then, in the liver, enzymatic
degradation to water and carbon dioxide (5).
Therefore, uncrosslinked HA solutions do not
provide the persistence required of a dermal filler
(6)."
-S
100% this as I mentioned. Crosslinked....
What's being sold is a plant based HA powder.
If it's dosed right (near juvederm dosages) mixed HA takes awhile to look safe for injection. I'm talking hours to look "dissolved"
The amount of HA must be pretty low if it dissolves quick into solution. Is this product ready to inject after mixing? Regardless though...its not crosslinked. It's not gonna last in the body long enough to "attach" to muscle fibers. Watch...after all this cross linking talk. Suddenly he's gonna say it is crosslinked, or come out with an ADVANCED formula.
Forgive my ignorance on this topic, but would it be possible to purchase "crosslinked" hyaluronic acid powder?
Or is the "cross-linking" process something that would have to be done to the already formulated powder?