I am if a bit of an outlier here as I don't have a thyroid gland. It was removed in 2005. I had 2 benign nodules and a thyroid goiter. Non cancerous but endo said a risk of changing to cancer 20 years down the road. Thyroid levels were perfect at the time too.
I am on 336 mg a day of tirosint gel cap T4 for those that have issues with binders in synthroid. Endo never tests anything but free t4 and TSH. I would recommend a wellness clinic as most traditional endos won't prescribe T4 for even subpar thyroid levels.
50 to 100mcg would be the sweet spot I would think. All T4 meds need to be taken on an empty stomach. I had problems converting as well as the dose they started me on was 175 mcg synthroid. I would pop it in the am then drink coffee. It wasn't until I started taking it at 3 am and drinking 32 Oz water that it kicked in. We ended up at 450 mcg on the synthroid but feel better on 336 of the tirosint.
He keeps me very high on free T4 and low on TSH.
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