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The Other Side of GLPs

This would almost be comical if big food and big pharma got into a battle who can win over the fatties...and also illustrates the point many have made. Without actual discipline and lifestyle changes...these drugs are nothing more than a bandaid. Give a man a fish vs teach a man to fish.
I’m not sure it matters much to big food / big ag / big pharma who wins, as mostly the same big banks, funds and whales own them all.
 
True I just contradicted myself there. I know when I was on it, eating 2k calories of lean meat was much more difficult as opposed to just a few protein bars then calling it a day.

2k lean meat only or with veggies? I used to be able to psmf but I guess now that I'm older...that constipation...holy hell.

Random question for anyone...why was t3 never used/trialed/became a thing as far as being a cure for obesity? I was just doing a search on thyroid hormones because my tsh is high and t4 low...and saw posts of dudes saying t3 melted fat off them. I guess fat people the surplus is so large t3 won't make a dent?
 
2k lean meat only or with veggies? I used to be able to psmf but I guess now that I'm older...that constipation...holy hell.

Random question for anyone...why was t3 never used/trialed/became a thing as far as being a cure for obesity? I was just doing a search on thyroid hormones because my tsh is high and t4 low...and saw posts of dudes saying t3 melted fat off them. I guess fat people the surplus is so large t3 won't make a dent?
1. Use and abuse of your thyroid can fuuuck you up. Heart problems, seizures, lots of bad shit.
2. Huge potential for misuse which can cause crazy hormone imbalances and fuck up normal body functions.
3. Risks out weight the benefits, hugely
4. We know that massive goal with any obesity treatment is lose preferentially body fat while minimizing muscle loss. 1/2 of the clueless remarks on GLP1s have been about muscle loss…and we know t3 eats everything in its path.

Obesity is a NEW human problem. So looking at something like cytomel, which came in the 80s and was never created for anything of the sort, probably willl never get a good look. It seems like most of the obesity fighting drugs either attack appetite or the body’s ability to digest…rather than just jacking up someone metabolism up.
 
1. Use and abuse of your thyroid can fuuuck you up. Heart problems, seizures, lots of bad shit.
2. Huge potential for misuse which can cause crazy hormone imbalances and fuck up normal body functions.
3. Risks out weight the benefits, hugely
4. We know that massive goal with any obesity treatment is lose preferentially body fat while minimizing muscle loss. 1/2 of the clueless remarks on GLP1s have been about muscle loss…and we know t3 eats everything in its path.

Obesity is a NEW human problem. So looking at something like cytomel, which came in the 80s and was never created for anything of the sort, probably willl never get a good look. It seems like most of the obesity fighting drugs either attack appetite or the body’s ability to digest…rather than just jacking up someone metabolism up.
That definitely makes sense...especially after I watched a good video where Scott talks about thyroid...he brings up many of the same points.


From what you've seen do you feel like thyroid use among bodybuilders is less common than 10, 20 years ago? Seems like I'd see it mentioned a ton on boards in the 2000s...now days rarely
 
That definitely makes sense...especially after I watched a good video where Scott talks about thyroid...he brings up many of the same points.


From what you've seen do you feel like thyroid use among bodybuilders is less common than 10, 20 years ago? Seems like I'd see it mentioned a ton on boards in the 2000s...now days rarely
I am not the other one but been on the boards for a long time and ya back in the day it was pretty common to see cats on 100 to 200 mcg of cytomel a day. Also used to see a lot higher clen and ephedrine dosages.
 
1. Use and abuse of your thyroid can fuuuck you up. Heart problems, seizures, lots of bad shit.
2. Huge potential for misuse which can cause crazy hormone imbalances and fuck up normal body functions.
3. Risks out weight the benefits, hugely
4. We know that massive goal with any obesity treatment is lose preferentially body fat while minimizing muscle loss. 1/2 of the clueless remarks on GLP1s have been about muscle loss…and we know t3 eats everything in its path.

Obesity is a NEW human problem. So looking at something like cytomel, which came in the 80s and was never created for anything of the sort, probably willl never get a good look. It seems like most of the obesity fighting drugs either attack appetite or the body’s ability to digest…rather than just jacking up someone metabolism up.
Great post. I am on replacement T4 for many years now. No self respecting endo will touch T3 unless it's under very special circumstances for short term use. Way too many risks and sides in even the normal population.
 
Great post. I am on replacement T4 for many years now. No self respecting endo will touch T3 unless it's under very special circumstances for short term use. Way too many risks and sides in even the normal population.
Same here,, doctor prescribed, t4 replacement dose which is 100mcg now. I won't touch t3 with a ten foot pole.
 
Great post. I am on replacement T4 for many years now. No self respecting endo will touch T3 unless it's under very special circumstances for short term use. Way too many risks and sides in even the normal population.
Not to get the thread too far off topic about glp, but I'd be interested in hearing about your t4 experience. Did labs say your tsh was high and t4 low? Did your endo or gp approve t4 or did you have to go the wellness clinic route? Has the t4 helped not just feeling better but also staying leaner easier? Any help appreciated I got some thyroid issues myself
 
Not to get the thread too far off topic about glp, but I'd be interested in hearing about your t4 experience. Did labs say your tsh was high and t4 low? Did your endo or gp approve t4 or did you have to go the wellness clinic route? Has the t4 helped not just feeling better but also staying leaner easier? Any help appreciated I got some thyroid issues myself
I am if a bit of an outlier here as I don't have a thyroid gland. It was removed in 2005. I had 2 benign nodules and a thyroid goiter. Non cancerous but endo said a risk of changing to cancer 20 years down the road. Thyroid levels were perfect at the time too.
I am on 336 mg a day of tirosint gel cap T4 for those that have issues with binders in synthroid. Endo never tests anything but free t4 and TSH. I would recommend a wellness clinic as most traditional endos won't prescribe T4 for even subpar thyroid levels.
50 to 100mcg would be the sweet spot I would think. All T4 meds need to be taken on an empty stomach. I had problems converting as well as the dose they started me on was 175 mcg synthroid. I would pop it in the am then drink coffee. It wasn't until I started taking it at 3 am and drinking 32 Oz water that it kicked in. We ended up at 450 mcg on the synthroid but feel better on 336 of the tirosint.
He keeps me very high on free T4 and low on TSH.
Screenshot_20250317_163017_Chrome.jpg
 
I am if a bit of an outlier here as I don't have a thyroid gland. It was removed in 2005. I had 2 benign nodules and a thyroid goiter. Non cancerous but endo said a risk of changing to cancer 20 years down the road. Thyroid levels were perfect at the time too.
I am on 336 mg a day of tirosint gel cap T4 for those that have issues with binders in synthroid. Endo never tests anything but free t4 and TSH. I would recommend a wellness clinic as most traditional endos won't prescribe T4 for even subpar thyroid levels.
50 to 100mcg would be the sweet spot I would think. All T4 meds need to be taken on an empty stomach. I had problems converting as well as the dose they started me on was 175 mcg synthroid. I would pop it in the am then drink coffee. It wasn't until I started taking it at 3 am and drinking 32 Oz water that it kicked in. We ended up at 450 mcg on the synthroid but feel better on 336 of the tirosint.
He keeps me very high on free T4 and low on TSH.
View attachment 221929
Good info thank you, those labs...a++
 
Random question for anyone...why was t3 never used/trialed/became a thing as far as being a cure for obesity? I was just doing a search on thyroid hormones because my tsh is high and t4 low...and saw posts of dudes saying t3 melted fat off them. I guess fat people the surplus is so large t3 won't make a dent?
Come on man, I really feel like you know the answer to this with how long you’ve been on the forums
 
Come on man, I really feel like you know the answer to this with how long you’ve been on the forums
Dont even respond to him. He asks questions like he's brand new here lol. it's a waste of time.
 
I am if a bit of an outlier here as I don't have a thyroid gland. It was removed in 2005. I had 2 benign nodules and a thyroid goiter. Non cancerous but endo said a risk of changing to cancer 20 years down the road. Thyroid levels were perfect at the time too.
I am on 336 mg a day of tirosint gel cap T4 for those that have issues with binders in synthroid. Endo never tests anything but free t4 and TSH. I would recommend a wellness clinic as most traditional endos won't prescribe T4 for even subpar thyroid levels.
50 to 100mcg would be the sweet spot I would think. All T4 meds need to be taken on an empty stomach. I had problems converting as well as the dose they started me on was 175 mcg synthroid. I would pop it in the am then drink coffee. It wasn't until I started taking it at 3 am and drinking 32 Oz water that it kicked in. We ended up at 450 mcg on the synthroid but feel better on 336 of the tirosint.
He keeps me very high on free T4 and low on TSH.
View attachment 221929
Where does your ft3 sit typically?
 
I get your perspective and I'll share mine in return. And I'm being completely serious.

My grandfather smoked and one time someone told him 'Don't you know those are going to take years off the end of your life?' He replied, 'Those are the nursing home years and I don't need them anyway.' He died at 89, at home, of natural causes, and smoked for 74 of those years. He never was on a prescription, never had a surgery, never had any health issues. The robust genetics of the men in my family are a big reason I can push bodybuilding as hard as we do.

We all know how this journey ends so you might as well have fun with it rather than playing it safe thinking you'll be the one who gets away.

I'll leave it be...but this comment has haunted me. I think I've gone back and read it as well as his PM's several times. I'm still really struggling with his passing. That's all I came here to say.
 
I'll leave it be...but this comment has haunted me. I think I've gone back and read it as well as his PM's several times. I'm still really struggling with his passing. That's all I came here to say.
While I know it changes nothing I can tell you that there’s nobody it has gotten to more than me as it was a reply to my post.

What I can also say is that his reply was not the end of that conversation amongst us. We continued that discussion privately further. As everyone knows here I am not shy and speak my mind on things, especially around health. Dan was the same way, so you can only imagine our discussions. 😂

Dan was 💯 confident in his choices and decisions around this subject. I spoke my mind, he listened and then in return spoke his. At the end of the day that’s all any of us can really do.

I started a thread on here a while back titled something along the lines of “will it be worth it”. I believe that is a question each of us needs to honestly ask ourselves every day in this sport.

But I can say for certain if Dan were still here he would come on here with some hard ass comment about how we need to get back to work. 😂 That’s what I intend to do while continuing to do this sport as responsibly as possible.
 

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