Doesn’t too much vitamin c cause hardening of the arteries?Dangers of megadosing:
"
Side effects of vitamin C
- Abdominal cramping
- Gas and bloating
- Diuretic effect
- Headache
- Kidney disease
- Increases iron absorption which is dangerous for hemochromatosis disorder
- May affect blood sugar levels in diabetics
- Risk for those with corn allergy
- Possible drug interactions with chemotherapy medications, nonsteroidal anti-inflammatory drugs (NSAIDs) including aspirin, acetaminophen (Tylenol), warfarin, tetracycline, protease inhibitors, birth control pills, and antacids containing aluminum"
How Much Vitamin C Is Too Much? The Hidden Dangers - Superfoodly
It's possible to have side effects and overdose on vitamin C. Megadoses aside, even daily intake of 1,000 mg has been linked to kidney damage.www.superfoodly.com
If youre taking steroids, I would be concerned about the hemochromatosis.
Yeah. My body is pissed at me. Genetically I’m blessed though. My grandma has had health issues since she was 30. She’s 96 now. My dad has cancer and diabetes but he’s still kicking along.25mg Losartan daily keeps my blood pressure perfect. Sometimes I need to take half of that or skip a day so it doesn't get too low. John when you joined this forum, your kidneys weren't in good shape. I hope you get this figured out soon!
Bad idea:Yeah. My body is pissed at me. Genetically I’m blessed though. My grandma has had health issues since she was 30. She’s 96 now. My dad has cancer and diabetes but he’s still kicking along.
I’m just glad I’m realizing that you guys still lift hard and heavy while on bp meds and you’re not getting constant injuries like I did on clonidine. I thought they all would be the same bad news for the gym.
My order of telmisartan just got approved so when it arrives I’ll take 80mg telmisartan and 10mg lisinopril. Studies show taking both is superior to one alone for bp. Until it arrives I’ll keep taking Nebivolol with lisinopril.
How have you been doing, Bio?
The June 2014 edition of Drug Safety Update highlighted a European safety review into dual therapy with an ACE inhibitor plus an ARB. This review concluded that no significant benefits of dual therapy were seen in people who did not have heart failure and there was an increased risk of hyperkalaemia, hypotension, and impaired renal function. [...]
My worst ever bp was 176/120. On the telmisartan with amlodipine at my last appointment it was 118/76Yeah. My body is pissed at me. Genetically I’m blessed though. My grandma has had health issues since she was 30. She’s 96 now. My dad has cancer and diabetes but he’s still kicking along.
I’m just glad I’m realizing that you guys still lift hard and heavy while on bp meds and you’re not getting constant injuries like I did on clonidine. I thought they all would be the same bad news for the gym.
My order of telmisartan just got approved so when it arrives I’ll take 80mg telmisartan and 10mg lisinopril. Studies show taking both is superior to one alone for bp. Until it arrives I’ll keep taking Nebivolol with lisinopril.
How have you been doing, Bio?
When i first made the decision to get my ass to the doctor,about 3 years ago, mine was 210/160 i shit you not. Doctor was very concerned lol. What made it worse was i knew i would need to tell him about my steroid use and i hate hospitals, doctors,,white coat syndrome. I was on 500 test and 600 tren E 100mg a day of adrol also. The reason i went is come to find out i was developing bronchitis and i felt like shit. Anyways that was a turning point for me, blood pressure meds cardio and lower doses from there on.My worst ever bp was 176/120. On the telmisartan with amlodipine at my last appointment it was 118/76
Doc told me its from age, genetics and the damn steroids lol.Wow, everytime a thread like this comes up, I'm really suprised by how many guys on this board are on BP medicine, I would be scared shitless to juice after being put on BP meds.
Do you guys have high BP from genetic factors or lifestyle/bodyweight factors?
My friend said Nebivolol made his fasting glucose go way up. He keeps telling me not to use it. Do you agree or disagree with this?Bad idea:
Renin-angiotensin system drugs: dual therapy | Advice | NICE
www.nice.org.uk
In case Telmisartan alone does not provide sufficient blood pressure control, then a beta-blocker or CCB can be added. You seem to not tolerate CCBs, so a beta blocker like Nebivolol would be the best choice. You should need no more than 80mg Telmisartan and 5mg Nebivolol to achieve an optimal blood pressure (~120-80).
It’s genetic for me but when I weigh 50Lbs less and don’t use AAS, and eat flawlessly clean, then my bp is 125/85. Both of my parents are on bp meds.Wow, everytime a thread like this comes up, I'm really suprised by how many guys on this board are on BP medicine, I would be scared shitless to juice after being put on BP meds.
Do you guys have high BP from genetic factors or lifestyle/bodyweight factors?
This is the study I saw about combining telmisartan and lisinopril. Although, it is on diabetics. Diabetes runs in my family.Bad idea:
Renin-angiotensin system drugs: dual therapy | Advice | NICE
www.nice.org.uk
In case Telmisartan alone does not provide sufficient blood pressure control, then a beta-blocker or CCB can be added. You seem to not tolerate CCBs, so a beta blocker like Nebivolol would be the best choice. You should need no more than 80mg Telmisartan and 5mg Nebivolol to achieve an optimal blood pressure (~120-80).
Totally disagree. Several studies have shown that cardioselective beta blockers, and Nebivolol specifically, do not increase blood glucose levels at clinical dosages.My friend said Nebivolol made his fasting glucose go way up. He keeps telling me not to use it. Do you agree or disagree with this?
Long-term Effects of the Novel [beta]-blocker, Nebivolol, on Blood Glucose in Hypertensive Patients Adverse effects on blood gluco Adverse effects on blood glucose (BG) are a concern with conventional [beta]-blockers1. Effects on BG of the novel, vasodilatory, selective [beta]1-blocker2, nebivolol, were evaluated during a long-term extension study in mild-to-moderate hypertensive patients (sitting diastolic blood pressure [SiDBP] [ge]95 and [le]109mmHg).
Patients who successfully completed one of three randomized, placebo-controlled, double-blind, 12-week, nebivolol dose-ranging studies entered a 9-month, open-label study, receiving once-daily nebivolol (5, 10 or 20 mg up-titrated to achieve BP goal). After 28 days, non-responders (average SiDBP [ge]90 mmHg and/or heart rate [lt]55 bpm) received nebivolol + open-label adjunct therapy (thiazide diuretic [[plusmn] triamterine] or other anti-hypertensives). BG levels were evaluated at baseline, 3, 6 and 9 months.
A total of 845 patients were treated: the majority received nebivolol monotherapy (N=607); nebivolol + diuretics (N=206); nebivolol + other (N=32, mostly amlodipine). Diabetic patients comprised 6.3% of the total, obese patients (BMI [ge]30) 42.0% and black patients 23.3%. Mean changes from baseline in BG (mg/dL) at 3, 6 and 9 months (95% confidence interval) were, respectively: nebivolol monotherapy 2.21 ([minus]0.01, 4.43), 3.26 (0.76, 5.75) and 0.74 ([minus]1.55, 3.03); nebivolol + diuretics 6.05 (2.00, 10.10), 8.27 (4.79, 11.74) and 7.42 (4.20, 10.64). Small sample size in the nebivolol + other group precluded meaningful interpretation of the results. Clinically significant BG increases were seen only in patients treated with adjunctive diuretics, which was likely due to the diuretics3. Long-term nebivolol treatment with or without adjunct therapy continued to significantly reduce BP and was well tolerated without typical [beta]-blocker side effects (e.g. fatigue, sexual dysfunction).
Unlike other [beta]-blockers, long-term nebivolol treatment has no effect on BG levels in hypertensive patients, confirming its persistently neutral glycemic effects.
In this multicenter trial, the effects of nebivolol added to an angiotensin-converting enzyme (ACE) inhibitor or angiotensin II receptor blocker (ARB) were assessed in patients with hypertension (diastolic blood pressure [DBP] 80-110 mm Hg) and prediabetes (fasting blood glucose 100-125 mg/dL and/or 2-hour oral glucose tolerance test [OGTT] 140-199 mg/dL). After a 4-week run-in period (in which lisinopril [10 mg/d] or losartan [50 mg/d] treatment was initiated), patients with DBP 90-110 mm Hg were randomized (2:2:1) to 12-week, double-blind treatment with nebivolol (n=223; 5-40 mg/d), hydrochlorothiazide (HCTZ; n=212; 12.5-25 mg/d), or placebo (n=102), titrated to achievement of 130/80 mm Hg. The primary outcome measure was DBP (last observation carried forward, intent to treat population); secondary measures included systolic blood pressure (SBP) and glucose levels. At baseline, overall mean values for body mass index, triglycerides, and high-density lipoprotein cholesterol were 32.3 kg/m(2) , 1.7 mmol/L, and 1.3 mmol/L, respectively. At week 12, nebivolol and placebo groups demonstrated a decrease of -9.4 and -5.0 mm Hg, respectively (P<.001) for DBP and -10.4 and -7.8 mm Hg for SBP (P=.147). The mean changes in area under the curve OGTT were 0.0 mg/dL (nebivolol), 6.9 mg/dL (HCTZ; P=.024 vs nebivolol), and -1.0 mg/dL (placebo). Adverse event-related discontinuation rates were 10.3%, 6.6%, and 2.0%, respectively. Nebivolol, added to an ACE inhibitor or ARB, provides additional blood pressure reduction with little or no effect on glucose metabolism in hypertensive patients with prediabetes.
Thank you. I think my friend is so paranoid he isn’t logical a lot of the time. His elevated blood glucose was most likely from crappy diet.Totally disagree. Several studies have shown that cardioselective beta blockers, and Nebivolol specifically, do not increase blood glucose levels at clinical dosages.
Effects of add-on nebivolol on blood pressure and glucose parameters in hypertensive patients with prediabetes - PubMed
In this multicenter trial, the effects of nebivolol added to an angiotensin-converting enzyme (ACE) inhibitor or angiotensin II receptor blocker (ARB) were assessed in patients with hypertension (diastolic blood pressure [DBP] 80-110 mm Hg) and prediabetes (fasting blood glucose 100-125 mg/dL...www.ncbi.nlm.nih.gov
Wow, everytime a thread like this comes up, I'm really suprised by how many guys on this board are on BP medicine, I would be scared shitless to juice after being put on BP meds.
Do you guys have high BP from genetic factors or lifestyle/bodyweight factors?
You would surely be more healthy. Give it a try. Just go on TRT and see how you do. Give it one year. If youre really that unhappy then you can go back on and gain it all back. Muscle memory is a real phenomenon. What you lose in 1 year you could probably gain back in about 6 months. Are you really gaining a lot of muscle right now or has that stalled? Stopping now wont be that bad. Youll be surprised at how much muscle you retain. Youre not going to look like you did before you started everything.But I also could stop everything and lose 30 pounds and maybe I wouldn’t need any bp meds, but would I be happy, hell no. I don’t know lol