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Berberine and protein degradation?

powerof2

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Atrogin-1 affects muscle protein synthesis and degradation when energy metabolism is impaired by the antidiabetes drug berberine. ... RESULTS: Berberine administration decreased protein synthesis and increased degradation in muscles of normal and db/db mice.

Without post the hole study. I couldn’t find the answer in a search. I’m sure it has been beaten down already. So before I throw my berberine in the garbage. What’s the take on this.


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You can offset this by heavy resistance training.
 
I have been using metformin and berberine for around 16 months. Can’t say I have gotten big change in a year. I stay lean.


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No need to use it post-workout.

And using Berb and metformin together isn't recommended together.
 
Are you using AAS? Pretty sure they will offset the berberine affects on protein synthesis
 
Are you using AAS? Pretty sure they will offset the berberine affects on protein synthesis

Not if it is totally alters/stopping the mechanism for a period of time. I would agree that it isn’t because I take that multiple times a day and have definitely kept everything while losing fat.
 
Taking plenty ass and Gh. I just don’t know that when it says it block mtor how much of it can be brought back with ass training ect


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