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I agree with GERM. Have used it both ways, and maybe there's only a hair in it, but I liked throwing it in twice a week. Same as test E. I think last time I used it, for instance, I was using ~800mg test E and ~600mg eq so splitting it into two also meant I got to rotate sites nicely with less volume as I was using pretty much delts only.
you'd be more than safe using only once a week, though. IronMike
PS - on dosing, I've found one of the best things with eq is I could easily go relatively high with no sides at all. I go lower with nandro products.