- Joined
- Feb 13, 2004
- Messages
- 4,374
Actually it's not.^ I assume you meant +.1ml in a 10ml vial will be +1% benzyl alcohol, which basically works out correct (it is actually a tiny bit less than 1 percent if the vial is filled exactly with 10ml but yeah thats being pedantic).
Some notes...
It is extremely hard to kill bacteria with heat only. Also with benzyl alcohol or a combination of both.
The only way to ensure you clear the vial of bacteria is to filter with a .22 micron filter.
This will not filter out any virus in the vial. If a virus survives in the vial you are fucked.
"Dry-heat sterilization of parenteral oil vehicles.
Kupiec TC1, Matthews P, Ahmad R.
Author information
Abstract
The purpose of this study was to evalutate the effect of temperature and time on the dry-heat sterilization conditions of cottonseed, peanut and sesame-seed oils used as vehicles for parenteral drugs. The three oils were inidividually spiked wiht Bacillus subtilis spores and exposed to dry heat at four temperatures (150, 160, 170, and 180 deg C) for three different time intervals (one, 1.5 and two hours). Following inoculation and dry-heat sterilization, samples were placed in a laminar airflow hood and processed according to 71, "Sterility Tests" of the USP XXIV/NF 19 using thioglycolate broth and fluid D. The specimens were then placed into an incubator at 30 deg C and observed for three, five and seven days for bacterial growth. All tests were performed in triplicate. Positive and negative controls were conducted with each group. All three oils were found to be free of viable Bacillus subtilis following dry-heat sterilization at 150, 160, 170 and 180 deg C for one, 1.5 and two hours after incubation for seven days. The positive controls had no observed bacterial growth. Dry-heat sterilization of the three oils at 150 deg C for one hour appeared to be sufficient for time and temperature conditions. However, the authors recommend dry-heat sterilization procedures be validated for each product."
https://www.ncbi.nlm.nih.gov/pubmed/23986005
I always baked my UG gear and vented with needle after pulling it out of the oven, more so to help the reduce solvent levels and pain. Never ever would pop the top and inject from a UG vial. Most of the time depending on the carrier oil, the baked gear would be filtered into a sterile vial via .22um.
I gained tons of strength and size off of the baked goods so the arguments I have had over the years about "heat destroying the gear and making it inert"
are pointless. (Not directed at you MM) just a general statement.
The original IP was quoted as saying many times on Anabolex " dilute with salad oil and heat in spoon" LOL.
The worst gear I ever had was Test Cypionate Pharm grade made by Sandoz, had to bake it to get past the test flu.