On Humalog Cycle - Starting Metformin?

[heman4u]

On Week 4 of Humalog 15 IU Pre-Workout Cycle 5x weekly(Mon, Tue, Wed, Fri, Sat). Have not used Metformin yet. I did a bit of search n reading here and learned that I need to start from 250mg a meal and go up from there upto like 1500mg. I stopped slin Saturday and will be not using for 2-4 weeks. But, I am starting Metformin and like to use it forever from now. My purpose is insulin sensitivity, staying lean off-season, and longevity. I have a few questions. But, before that I will share my diet n daily plan:

7am: 3IU GH, 12.5mcg T3 n go for a brisk walk 30 mins

7:30: Meal 1, Oats n Chicken

10:30: Meal 2 Rice n Chicken

1:30: Meal 3 Rice n Beef

4pm: 3IU GH

4:30: Rice n Chicken

6:30: Insulin 15 IU with Shake 1

7pm: Start Workout

7:30: Shake 2

8:30: Workout ends, Shake 3

9:30 reaching home: Rice n Egg Whites

11:30pm: Oats n Egg Whites

12: Sleep

NOW, My questions are:

1) Which meals can I add metformin to? I am thinking to start Metformin at 250mg with Meal 1. Few days later add 250mg to Meal 3. Is it OK?

2) Once I have to increase the dose upto 1500mg daily, which other meals can I add it to?

3) Does the metformin timing matter when ON/OFF Insulin?

Please share your thoughts guys.

 

[suppdude]

Just know Metformin half life is roughly 6 hours. Metformin will block a percentage uptake of carbohydrates.

So keep your Metformin dose away from your slin dose.

Also be aware, Metformin can put a pretty good hault on appetite. So if you find your appetite is starting to decline at a higher dose, drop the dose.

 

[heman4u]

Just know Metformin half life is roughly 6 hours. Metformin will block a percentage uptake of carbohydrates.

So keep your Metformin dose away from your slin dose.

Also be aware, Metformin can put a pretty good hault on appetite. So if you find your appetite is starting to decline at a higher dose, drop the dose.

Thanks a lot bro suppdude. I read one should supplement with B12 when on Metformin. Any idea how it should be dosed?

 

[suppdude]

Thanks a lot bro suppdude. I read one should supplement with B12 when on Metformin. Any idea how it should be dosed?

500 mcg per day should suffice.

 

[heman4u]

500 mcg per day should suffice.

Can the B12 also solve the possible appetite suppression from Metformin?

 

[suppdude]

Can the B12 also solve the possible appetite suppression from Metformin?

No. Adding MK-677 could assist but I'd suggest just lowering dose if you get to 1500mg and find appetite isn't there. Gone up to 1500mg and it started killing appetite so dropped to 1g and still wasn't what wanted so went to 500mg and good there.