I had the weirdest, uncommon reaction to BP meds. The doctor put me on Amlodipine first and that made REALLY tense and angry, not like me. Then it was switched to Lisinopril which made feel the exact opposite, overly sensitive and emotional. Then I was put on Losartan and when I took it every other day it was ok but when I used it daily I started getting that agitated angry feeling again. Now I've worked up to every day again and for the most part it's ok. On occasion I'll start getting that feeling again and I usually skip a day or break the pill in half, it's 25mg. The doctor said she had never heard of those side effects before. I was only on 250 to 375mg of Test and a little Deca at the time too.