There definitely are guys who seem totally resilient to Tren. I have a bodybuilder whose lipids came back PERFECT, I mean, OUTSTANDING, after running Tren (acetate, then hexahydrobenzylcarbonate) at a moderately high dose for 12 weeks. I gave his wife a mood & anger questionnaire weekly. He was totally unaffected besides blowing the fuck up physically and strength-wise. No nightsweats. Then, there's guys at the total opposite end of the spectrum. I coach a guy in-person who at 100 mg weekly becomes a total cunt personality-wise, danger to society, sleep goes haywire, so does RHR, et cetera per his Whoop data. If I had any say in his protocol (unique circumstances) he wouldn't use tren.